Antibiotic resistance could undo a century of medical progress – but four advances are changing the story

New tools are changing the fight.

Good Partner

Apr 27, 2026

By Good Partner

April 27, 2026

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Photo credit: wildpixel/iStock via Getty Images Plus – Scientists are fighting back against antibiotic resistance with new strategies and tools.

André O. Hudson

Imagine going to the hospital for a bacterial ear infection and hearing your doctor say, “We’re out of options.” It may sound dramatic, but antibiotic resistance is pushing that scenario closer to becoming reality for an increasing number of people. In 2016, a woman from Nevada died from a bacterial infection that was resistant to all 26 antibiotics that were available in the United States at that time.

The U.S. alone sees more than 2.8 million antibiotic-resistant illnesses each year. Globally, antimicrobial resistance is linked to nearly 5 million deaths annually.

Bacteria naturally evolve in ways that can make the drugs meant to kill them less effective. However, when antibiotics are overused or used improperly in medicine or agriculture, these pressures accelerate the process of resistance.

As resistant bacteria spread, lifesaving treatments face new complications – common infections become harder to treat, and routine surgeries become riskier. Slowing these threats to modern medicine requires not only responsible antibiotic use and good hygiene, but also awareness of how everyday actions influence resistance.

Since the inception of antibiotics in 1910 with the introduction of Salvarsan, a synthetic drug used to treat syphilis, scientists have been sounding the alarm about resistance. As a microbiologist and biochemist who studies antimicrobial resistance, I see four major trends that will shape how we as a society will confront antibiotic resistance in the coming decade.

1. Faster diagnostics are the new front line

For decades, treating bacterial infections has involved a lot of educated guesswork. When a very sick patient arrives at the hospital and clinicians don’t yet know the exact bacteria causing the illness, they often start with a broad-spectrum antibiotic. These drugs kill many different types of bacteria at once, which can be lifesaving — but they also expose a wide range of other bacteria in the body to antibiotics. While some bacteria are killed, the ones that remain continue to multiply and spread resistance genes between different bacterial species. That unnecessary exposure gives harmless or unrelated bacteria a chance to adapt and develop resistance.

In contrast, narrow-spectrum antibiotics target only a small group of bacteria. Clinicians typically prefer these types of antibiotics because they treat the infection without disturbing bacteria that are not involved in the infection. However, it can take several days to identify the exact bacteria causing the infection. During that waiting period, clinicians often feel they have no choice but to start broad-spectrum treatment – especially if the patient is seriously ill.

Close-up of two pill capsules inscribed AOMXY 500 in a blister packet — Amoxicillin is a commonly prescribed broad-spectrum antibiotic. TEK IMAGE/Science Photo Library via Getty Images

But new technology may fast-track identification of bacterial pathogens, allowing medical tests to be conducted right where the patient is instead of sending samples off-site and waiting a long time for answers. In addition, advances in genomic sequencing, microfluidics and artificial intelligence tools are making it possible to identify bacterial species and effective antibiotics to fight them in hours rather than days. Predictive tools can even anticipate resistance evolution.

For clinicians, better tests could help them make faster diagnoses and more effective treatment plans that won’t exacerbate resistance. For researchers, these tools point to an urgent need to integrate diagnostics with real-time surveillance networks capable of tracking resistance patterns as they emerge.

Diagnostics alone will not solve resistance, but they provide the precision, speed and early warning needed to stay ahead.

2. Expanding beyond traditional antibiotics

Antibiotics transformed medicine in the 20th century, but relying on them alone won’t carry humanity through the 21st. The pipeline of new antibiotics remains distressingly thin, and most drugs currently in development are structurally similar to existing antibiotics, potentially limiting their effectiveness.

To stay ahead, researchers are investing in nontraditional therapies, many of which work in fundamentally different ways than standard antibiotics.

One promising direction is bacteriophage therapy, which uses viruses that specifically infect and kill harmful bacteria. Others are exploring microbiome-based therapies that restore healthy bacterial communities to crowd out pathogens.

Researchers are also developing CRISPR-based antimicrobials, using gene-editing tools to precisely disable resistance genes. New compounds like antimicrobial peptides, which puncture the membranes of bacteria to kill them, show promise as next-generation drugs. Meanwhile, scientists are designing nanoparticle delivery systems to transport antimicrobials directly to infection sites with fewer side effects.

Beyond medicine, scientists are examining ecological interventions to reduce the movement of resistance genes through soil, wastewater and plastics, as well as through waterways and key environmental reservoirs.

Many of these options remain early-stage, and bacteria may eventually evolve around them. But these innovations reflect a powerful shift: Instead of betting on discovering a single antibiotic to address resistance, researchers are building a more diverse and resilient tool kit to fight antibiotic-resistant pathogenic bacteria.

3. Antimicrobial resistance outside hospitals

Antibiotic resistance doesn’t only spread in hospitals. It moves through people, wildlife, crops, wastewater, soil and global trade networks. This broader perspective that takes the principles of One Health into account is essential for understanding how resistance genes travel through ecosystems.

Researchers are increasingly recognizing environmental and agricultural factors as major drivers of resistance, on par with misuse of antibiotics in the clinic. These include how antibiotics used in animal agriculture can create resistant bacteria that spread to people; how resistance genes in wastewater can survive treatment systems and enter rivers and soil; and how farms, sewage plants and other environmental hot spots become hubs where resistance spreads quickly. Even global travel accelerates the movement of resistant bacteria across continents within hours.

Together, these forces show that antibiotic resistance isn’t just an issue for hospitals – it’s an ecological and societal problem. For researchers, this means designing solutions that cross disciplines, integrating microbiology, ecology, engineering, agriculture and public health.

4. Policies on what treatments exist in the future

Drug companies lose money developing new antibiotics. Because new antibiotics are used sparingly in order to preserve their effectiveness, companies often sell too few doses to recoup development costs even after the Food and Drug Administration approves the drugs. Several antibiotic companies have gone bankrupt for this reason.

To encourage antibiotic innovation, the U.S. is considering major policy changes like the PASTEUR Act. This bipartisan bill proposes creating a subscription-style payment model that would allow the federal government up to US$3 billion to pay drug manufacturers over five to 10 years for access to critical antibiotics instead of paying per pill.

Global health organizations, including Médecins Sans Frontières (Doctors Without Borders), caution that the bill should include stronger commitments to stewardship and equitable access.

Still, the bill represents one of the most significant policy proposals related to antimicrobial resistance in U.S. history and could determine what antibiotics exist in the future.

The future of antibiotic resistance

Antibiotic resistance is sometimes framed as an inevitable catastrophe. But I believe the reality is more hopeful: Society is entering an era of smarter diagnostics, innovative therapies, ecosystem-level strategies and policy reforms aimed at rebuilding the antibiotic pipeline in addition to addressing stewardship.

For the public, this means better tools and stronger systems of protection. For researchers and policymakers, it means collaborating in new ways.

The question now isn’t whether there are solutions to antibiotic resistance – it’s whether society will act fast enough to use them.

This article originally appeared on The Conversation. You can read it here.

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Photo credit: Canva – A woman intensely exercises, left, and a morning stretch, right.

Care, Health

More women are rejecting ‘optimization culture’ for realistic wellness plans

Feel great and be happy.

Mark Wales

5/16/2026

Being fit used to mean getting enough sleep, drinking more water, and moving your body, perhaps in a daily walk. With the explosion of social media and digital self-help trends, finding an acceptable level of wellness can feel like stepping into a full-time job with daily performance reviews.

For many women, what started as self-care has slowly become another exhausting form of self-optimization. And increasingly, they’re pretty much done with it. According to Women’s Business Daily, one of the biggest wellness shifts happening right now is a move away from extreme routines. Women want habits that actually fit into real life.

An intense workout.
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Wellness feels like a full-time job

Instead of chasing perfection, more women are choosing what can be described as a more realistic approach to wellness, incorporating sustainable routines built around balance and emotional well-being rather than climbing a never-ending ladder of constant improvement.

The shift comes after a solid decade of what many refer to online as “optimization culture.” This exhausting idea assumes that every part of life needs to be carefully measured, improved, and optimized.

Experts believe this mindset is not only making people miserable; it’s unsustainable.

An exhausting routine.
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A backlash against the “always improve yourself” culture

A recent article in Psychology Today found that “wellnessmaxxing” trends turn self-care into another form of anxiety. This is especially true when routines become so demanding that people feel more guilt than relief. As creators post TikToks showing themselves “maxing out” in some kind of self-congratulation, they spread unhelpful expectations that no longer promote self-care.

Verywell Health explains that these influencers broadcast an all-consuming performance metric. People now face a painful realization that they can never do enough. It’s hard to miss the irony that wellness has begun to feel unhealthy.

Women are increasingly embracing low-pressure routines instead of overly aspirational ones. Think walks instead of cross-training, and a morning meditation instead of a week-long stay at a Tibetan monastery. It’s okay to just eat more vegetables instead of a perfectly balanced daily nutrition plan of 150 grams of protein, wheatgrass smoothies, and specifically rated pH-balanced alkaline water.

After all the extreme exercises, self-help books, and sophisticated meal plans, it’s time to get back to basics. Here’s one version of a realistic plan: drink some water, get outside, and try to sleep a little better.

A casual walk with a dog.
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Getting back to the basics

A beauty editor writing for Who What Wear documented her attempt to follow a social-media-inspired wellness reset. With all the expensive and complicated habits she hoped would unlock the “incredibly high-functioning, ultra-productive version” of herself, she came away understanding that she should stick with the basics.

Modern life already asks women to juggle careers, caregiving, appearance standards, finances, and relationships. Somewhere along the journey, wellness became just one more category to add to the pile.

Maintaining a perfect life balance.
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Women are choosing simple, sustainable routines

Finding realistic wellness is a trend that reflects a growing desire for community-centered wellness rather than isolated self-improvement. Instead of wellness looking like a solo pursuit for an achievement award, many women are leaning toward connection: walking groups, shared meals, accountability with friends, and being honest about feeling burned out on all of it.

The Times reports that people feel walking groups are less intimidating and more emotionally supportive. People don’t just want fitness; they want to belong to something.

A 2025 study in Frontiers in Psychology focused on the benefits of women finding social support groups. Programs that incorporated women’s preferences into their daily lives were more likely to be enjoyed and maintained.

Wellness cultures have told women the answer is to do more: more discipline, more self-reflection, more perfect sleep, more work dedication, more family direction, more effort.

Making life more enjoyable and realistic can help well-being feel easier to maintain. A joyful life is better lived “in” than constantly measured “against” unrealistic expectations.

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Photo credit: MoMo Productions/DigitalVision via Getty Images – Emphasizing the sounds of certain words to young children can help them retain language, not confuse them about speaking properly.

Health, Research

Is baby talk bad? Why ‘parentese’ actually helps babies learn language

Sing-song speech can support early language growth.

Good Partner

5/15/2026

Karen Stollznow

Many parents have heard the warning: Don’t use baby talk with babies and toddlers. Instead, caregivers are often encouraged to speak properly and use adultlike language, out of concern that simplified speech could confuse children or delay language development.

But my research, which I highlighted in in my new book, “Beyond Words,” suggests the opposite is true. The sing-song voice many adults instinctively use with infants, sometimes called “baby talk” but more accurately known as “parentese” or infant-directed speech, actually helps children learn language.

Far from confusing babies, exaggerating phrases like “Loooook at the doggie!” capture their attention, help them detect patterns in speech and strengthen social bonding.

And the funny mistakes children make along the way, such as saying “goed,” instead of “went,” or “mouses” instead of “mice,” are not signs that children are learning language incorrectly. They are evidence that children are actively working out the rules of language for themselves.

Speaking ‘parentese’ to a child doesn’t involve nonsense words. BjelicaS/E+ via Getty Images

What parentese really is

When many people think of baby talk, they imagine nonsense phrases like “goo goo ga ga” or made-up words like “num nums.” But that’s not what linguists and developmental psychologists mean by parentese.

Parentese uses real words and grammatically correct sentences, but with exaggerated intonation, a higher pitch, stretched-out vowels and a slower rhythm. Think of the way a caregiver might naturally say: “Hi, baaaaby! Are you huuungry?”

There is little evidence that occasional playful nonsense words harm children’s language development. But studies suggest that parentese in particular helps babies pay attention to speech, recognize patterns and engage socially.

Adults across cultures tend to speak this way to infants instinctively. Even people who swear they never use baby talk often slip into it around babies.

Researchers have found that infants actually prefer listening to parentese over regular adult speech. The exaggerated sounds and slower pacing make language easier to process. Babies are better able to pick out individual sounds, notice word boundaries and recognize patterns. In other words, parentese helps tune babies into language.

It also strengthens emotional connection. Language learning does not happen in isolation. Babies learn through warm, responsive interaction with caregivers during feeding, play, bath time and everyday routines.

Interestingly, humans are not the only ones who respond to this style of communication. Studies have even shown that cats react more positively when people use a baby-talk voice with them.

Babies are not passive learners

Children do not learn language simply by copying adults word for word. They actively test hypotheses about how language works. That is why toddlers make predictable and surprisingly logical mistakes.

One common example is overgeneralization. A child learns that people form the past tense of many verbs by adding “-ed,” so they produce forms like “goed,” “eated” or “comed.”

These are not random errors. In fact, they show that the child has understood a grammatical rule and is trying to apply it consistently. The problem is simply that English is full of irregular exceptions. The same thing happens with plurals. Children may say “foots” instead of “feet” or “mouses” instead of “mice.” Again, the logic behind these errors is sound.

Linguists sometimes say that children are little scientists, constantly testing patterns and revising their understanding as they receive more input from the world around them.

Why toddlers call everything a ‘dog’

Young children also make predictable mistakes with meaning.

A toddler might learn the word “dog” and then use it for every four-legged animal they encounter. Linguists call this overextension. On the flip side, some children use words too narrowly. A child may use “dog” only for the family pet and not recognize that other dogs belong in the same category. Linguists call this tendency underextension.

These mistakes reveal how children organize and categorize the world around them. They are gradually mapping words onto objects, people and experiences.

Pronouns are another tricky area. Small children often confuse “me” and “you” because these words constantly shift depending on who is speaking. If a parent says, “I’ll pick you up,” the child hears themselves called “you.” But when they try to repeat the sentence, they may not yet understand that the labels switch from speaker to speaker.

This is why toddlers sometimes say things that sound unintentionally cute or confusing. But beneath the confusion is a sophisticated learning process.

Even the Cookie Monster gets it wrong

Children’s speech errors are so recognizable that they often appear in popular culture. Sesame Street’s character Cookie Monster famously says things like “Me want cookie,” while Elmo often refers to himself in the third person: “Elmo wants this.” These speech patterns mirror real stages of child language development. Young children commonly confuse pronouns or refer to themselves by name before mastering forms like “I,” “me” and “mine.”

Despite occasional complaints from adults, there is no evidence that hearing this kind of speech harms children’s language development. If anything, it reflects the natural experimentation children go through.

The Cookie Monster saying ‘Me want cookie’ won’t teach babies and young kids to speak incorrectly. Brian Killian/WireImage via Getty Images

‘Pasketti’ and ‘wabbit’

Pronunciation develops gradually too. Young children often simplify difficult sounds and groups of consonants. “Spaghetti” becomes “pasketti,” “rabbit” becomes “wabbit” and “yellow” may come out as “lellow.”

Speech-language specialists call these simplifications phonological processes. They are a normal part of development because some sounds are physically harder to produce than others. Sounds such as r, th, sh and ch tend to develop later because they require more precise control of the tongue and mouth.

Most children naturally outgrow these pronunciation patterns as their speech matures. However, persistent difficulties can sometimes signal a speech or language disorder, which may require professional support.

Children don’t learn language by copying adults word for word. They learn through interaction, experimentation and repetition. DrAfter123/DigitalVision Vectors via Getty Images

Mistakes are part of learning

Parents are often under enormous pressure to do everything right, including helping their children learn to speak a language. But children do not learn language by avoiding mistakes. They learn through interaction, experimentation and repetition.

Parentese helps babies focus on speech and engage socially. The funny mistakes toddlers make reveal that they are actively piecing together the complex system of language and are often signs of normal development. Language acquisition is messy, creative and remarkably sophisticated.

Speaking in an exaggerated sing-song voice to a baby is not something parents and caregivers need to feel embarrassed about.

Far from harming language acquisition, it may help lay the foundation for it.

This article originally appeared on The Conversation. You can read it here.

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Photo credit: Canva – Women enjoy a short walk.

Health, Well-being

People who dread working out are trying ‘micro walks,’ and the results feel great

Why doing less actually leads to more.

Mark Wales

5/15/2026

For many people, working out isn’t the hard part. It’s everything that comes with it: the time commitment, the pressure of consistency, and the feeling that only full workouts count.

That all-or-nothing mindset keeps a lot of people from even getting started. This might explain why a small idea has been gaining traction. Instead of setting aside an hour or two to exercise, people are taking “micro walks” instead.

Two women enjoy a quick “micro walk.”
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“Micro walks” are simple and still provide the benefits

A loop around the block in the morning. A quick break between meetings or events on the daily schedule. Perhaps another lap after dinner. These short walks sprinkled throughout the day might seem too simple to matter.

For a growing number of people, the simplicity is what makes it really work. Doing less at a time, but more often, is what’s resonating. The barrier to entry suddenly drops. People don’t need much motivation. Just a few minutes is enough to get started.

@baileeyy_nicole
micro walks are the move!!!
♬ Jazz Mood – Lady-M

The hidden appeal behind shorter walks

The appeal of a “micro walk” for people dreading a workout isn’t necessarily about peak optimization. The benefits come from gaining momentum. For individuals who have spent years feeling like they’re either all-in or completely off track, this offers a third option.

Short periods of exercise fit into the structure of real life instead of competing with it. Finding the time to set aside large blocks of time can be difficult for many people. Breaking movement into smaller increments makes it far more manageable.

In the end, consistency matters more than perfection. Getting daily steps in becomes something achievable rather than overwhelming.

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Research shows that shorter walks work

A 2024 study published in the Proceedings of the Royal Society B, a scientific journal recognized for its rigorous reviews, investigated the benefits of different walking patterns. The findings revealed that short walking bursts use more energy than longer continuous walks. Breaking up exercise is more impactful than it seems.

Harvard Health Publishing reported that even brief walks can boost energy and counteract the effects of prolonged sitting. Getting moving has significant heart health advantages, and walking is extremely accessible.

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Physical exercise boosts overall well-being

Turning short walks into a mental reset can boost a person’s emotional well-being. Physical exercise stimulates the body, yet it also increases inner harmony. A 2025 study published in Springer Nature found that even a 10-minute walk can meaningfully improve mood regulation. Finding the time for a brief walk can lessen symptoms of anxiety.

A 2024 study published in Nature demonstrated that short activity breaks increase cognitive performance and elevate mood. There are immediate emotional advantages to activities like “micro walks,” not just long-term fitness gains.

Science demonstrates that walking has both physical and emotional benefits. The most common barriers are time and motivation. Shifting from big goals to showing up in small, repeatable moments is what actually matters. “Micro walks” turn movement from something people have to make time for into something that becomes part of how they live. It’s another small step toward finding happiness.

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