Every evening, when it’s time to kick back after a busy day seeing patients, pain management physician Daniel Cartledge of Delray Beach, Florida, relaxes in a comfortable club chair and turns on his NERVANA, a device with earbuds that’s both a music player and a transcutaneous vagal nerve stimulator. More plainly, the earbuds send gentle electrical pulses, synced with the listener’s playlist of choice, through the ear to one of the most critical regulatory nerves in the body.


For Cartledge, using the NERVANA “takes away the background noise in my brain,” he says. “I feel relaxed and focused.” Along with his heart-surgeon brother, Richard, he developed the NERVANA, available to consumers in 90 countries. Cartledge’s invention is just one of a new wave of vagus nerve stimulators currently being studied or already in use, offering a variety of applications across a diverse range of ailments, from autoimmune diseases and depression to epilepsy and digestive disorders like Crohn’s.

Vagus in Latin means wandering, and that’s exactly what the vagus nerve does as it passes through the major organs. Originating in the brain stem and extending all the way down to the colon, the nerve regulates many important bodily functions. As part of the parasympathetic nervous system, often referred to as the “rest and digest system,” it can calm you down, and is responsible for that pleasant feeling of satiety and sedation after eating. It also helps regulate heart rhythm.

[quote position=”left” is_quote=”true”]Our nerves speak an electrical language, and they use that language to talk directly to cells.[/quote]

Vagus nerve stimulation (VNS) has been associated with many benefits, such as improved memory, immune function, sleep, and mood, as well as higher levels of growth hormone. VNS may also help tame inflammation, allergic responses, and tension headaches. There are over 30 clinical trials underway on the vagus nerve, many of which are testing for the success or failure of noninvasive stimulation gadgets like the NERVANA.

Here, a quick review of bioelectronics with great promise for several chronic conditions:

Rheumatoid Arthritis

An implantable device that stimulates the vagus nerve has been shown to improve rheumatoid arthritis, a painful autoimmune disease in which inflammation damages joints. Powerful medications can help tame the disabling pain and swelling of rheumatoid arthritis, often by quelling the production of an inflammatory molecule called TNF (tumor necrosis factor). In a 2016 study of 17 patients, a stimulation device was implanted and then activated and deactivated on a set schedule for 84 days. Several patients that had failed to respond to multiple medications had a strong response to the vagus nerve stimulator. TNF production was significantly inhibited, and no serious side effects were noted.

“This is more than a vagus nerve story, more than a TNF story, and even more than a rheumatoid arthritis story,” says one of the study’s authors, Kevin Tracey, M.D. of the Feinstein Institute for Medical Research in Long Island. “The big story here is that you can start with a molecular target such as TNF, and rather than screening or devising drugs to reduce it, you can target that molecule by using an electronic device.”

One might wonder, how does a device that stimulates a nerve manage to treat an autoimmune disease? Tracey points out that our nervous system has evolved to coordinate information from all the body’s cells in order to regulate them and keep them healthy. “Our nerves speak an electrical language, and they use that language to talk directly to cells,” he says.

The study needs to be repeated in a large group of patients in order to definitively prove its efficacy and ensure its safety, but Tracey believes that similar devices may eventually be used in a range of diseases involving inflammation—from hypertension to diabetes to inflammatory bowel disease.

Epilepsy, Depression, and Pain

An implantable device that stimulates the nerve has been shown to help prevent or reduce epileptic seizures, reduced by up to 40 percent, allowing patients to reduce their medication dosages. Surgically implanted devices last up to 10 years, though a new noninvasive device—the wearable ear electrode NEMOS—has been approved in Germany, Austria, and Italy for treating epilepsy, depression, and pain. Like NERVANA, NEMOS stimulates the vagus nerve through the ear, where a branch of the nerve surfaces in front of the ear canals.

In one study of 48 volunteers, which was double-blind placebo using either a sham device or NEMOS, active treatment reduced deep tissue pain as well as the perception of pain from mechanical stimulation. In another study of 10 epileptic patients with seizures that were not responsive to medication, vagus nerve stimulation for nine months reduced frequency of seizures in five patients. Major depressive disorder has also proven responsive; a study from Harvard Medical School and the China Academy of Chinese Medical Sciences found that patients who received real vagus nerve stimulation via an ear electrode showed significant improvement in depression, while those who received sham treatment did not improve.

Migraines

More than 28 million Americans suffer from migraine headaches, and nearly three-quarters of those are women. A double-blind placebo clinical trial of a vagus nerve stimulator called NET-1 demonstrated significant reduction in the frequency and intensity of migraines. Two subsequent three-month studies also showed significant improvement. Other studies on migraine and vagus nerve stimulation also demonstrated improvement. The device has since been improved and modified and is now called NET-1000. Both the NET-1000 and a NET-3000 device are available in the United States without any attached medical claims of safety or efficacy. A different version, the NET-2000, has received FDA approval as a Class III device by prescription only for indications of depression, anxiety, and insomnia.

[quote position=”full” is_quote=”true”]Rather than devising drugs to resolve a medical issue, you can use an electronic device.[/quote]

“There has been over thirty years of research on vagal nerve stimulation,” says Cartledge. And though his device makes no medical claims, and Cartledge does not use the NERVANA when treating his pain patients, he has been impressed with the effectiveness of “ear electroacupuncture” in his fibromyalgia patients. It turns out that some ancient ear acupuncture points, demonstrated to be effective for pain and constipation, overlap with the vagus nerve’s path. So we’ve been stimulating the vagus nerve without actually naming it for centuries—often without the help of a device.

Another gadget-free method for vagus nerve stimulation involves meditation: A 2013 study found that vagus function increased with a regular meditation practice. Study participants were randomly assigned to either a group that generated positive emotions via loving-kindness meditation or to a control group that did not meditate. Those who repeated silent phrases such as “May you feel safe, may you feel happy, may you feel healthy, may you live with ease” experienced a surge in vagal tone, as well as improvements to health throughout the body.

  • New Russian research suggests that the human lifespan could be up to 156 years
    Photo credit: CanvaResearchers found what's preventing us from living longer.
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    New Russian research suggests that the human lifespan could be up to 156 years

    Humans can live much longer if certain barriers are addressed.

    According to the Guinness Book of World Records, the oldest person lived to the ripe age of 122 years old. Such a lifespan is an incredible feat, but what if the average person could beat that record by 34 years? Recent research done in Russia has led scientists to believe that the average human lifespan could be up to 156 years.

    The researchers at Skoltech Biomed Technologies Center developed a mathematical model that allowed them to “switch on” a variety of aging mechanisms. This allowed them to calculate a human’s lifespan where mortality risk never increased with age. After experimenting with different scenarios and conditions, they found the biggest barriers to longevity were caused by non-renewable tissues and somatic mutations.

    What are these barriers against longer life?

    Somatic mutations are DNA changes within a cell. They accumulate over time during a human’s life and cannot be reversed with any existing therapy. These DNA errors that pile up in our cells contribute to the aging process.

    Many human organs like the liver and skin continually replace cells and regrow damaged portions of themselves. However, there are two organs that can’t do this: the brain and the heart. Brain tissue (neurons) and heart tissue (cardiomyocytes) cannot regenerate. This proves to be the most prominent biological limit that shortens our lifespans. This explains why issues like dementia and heart disease are prominent causes of death and morbidity later in life. Since those organs’ tissues don’t replace damaged cells, they’re prone to irrevocably decline over time.

    “The key finding of the study is the discovery of substantial differences between tissue types. Neurons and cardiomyocytes, which lack the ability to divide, turned out to be the main limiting factors: when all other causes of aging are eliminated, somatic mutations alone reduce the theoretical median lifespan from 1,759 years (for a hypothetical non-aging human organism) to 156 years,” said Evgeny Efimov, a research intern at the Skoltech Biomed Technologies Center, researcher at AIRI, and one of the key authors of the study.

    This suggests that somatic mutations and DNA damage is what ultimately prevents humans from living indefinitely, even if our brains and hearts regenerated cells like other organs.

    So what’s next?

    Now knowing these biological limitations, the researchers hope to study other areas of aging impacting the human lifespan that could plausibly be reversed. This includes mitochondrial dysfunction, telomere shortening, epigenetic drift, and loss of proteostasis. 

    The hope is to have a clearer priority list of issues for future therapies to tackle. This is not just to possibly extend life, but to improve lives in general. By developing a fully comprehensive theory of aging, Skoltech hopes to pinpoint which aspects of aging are within our scope to address. After all, thoroughly studying each puzzle piece that makes up human life gives us a better understanding of the whole.

    Of course, other impactful factors in a person’s lifespan can be addressed today. As most know, things like diet, sleep, and exercise are among them. A person’s living environment can also negatively impact their lifespan if it doesn’t have clean air, access to clean water, and so on.

    For now, the best method for living long is to follow instructions from your physician. Whether you make it to 156 years or not, living well is best for whatever time you’re given.

  • Screen time guidelines for kids and adolescents have shifted as research paints a more nuanced picture
    Photo credit: PeopleImages/iStock via Getty ImagesWhat kids are doing on tablets seems to matter more than how long they use them.

    Concerns surrounding young people’s screen time are widespread.

    Australia became the first country to ban social media for users under 16 in December 2025, and DenmarkFrance and the U.K. have since announced similar restrictions to begin this year.

    In the U.S., as of mid-2026, more than 30 states have passed laws banning or restricting cellphones in K–12 classrooms; in 2023, the U.S. surgeon general issued a formal advisory on social media and children’s and adolescents’ mental health; and bestselling books tell parents that smartphones are “rewiring” their children’s brains.

    These concerns and policies are part of a quickly changing national and international conversation around how young people spend time on screens and its relationship to their overall health and development. My reading of the mounting research on this issue across disciplines is that the popular narrative blaming screens and smartphones for an adolescent mental health crisis runs well ahead of the current evidence.

    I study adolescent digital media use and its influence on social, emotional and academic outcomes. A growing body of research suggests that one-size-fits-all solutions are not the answer and that managing appropriate use of digital media needs to take into account a child’s developmental milestones, how parents and adults around them use media, and the ways kids use it to connect and learn with friends and family.

    Screen time: From monolith to multifaceted

    Wide adoption of digital media and the internet broadened the range of experiences young people could have online. At the same time, the digital age introduced newfound uncertainties. As with the advent of radio, comic books and arcades, adults worried about how children might interact with or be affected by internet use.

    In response, the American Academy of Pediatrics first recommended in 1999 that parents and caregivers keep children under 2 away from screens. In the decades since, professional guidance largely treated children’s media use as a behavior to be mitigated.

    Policies introduced by the academy in 2013 and 2016 continued to advise that school-age kids and adolescents – those ages 5 to 18 – be restricted to no more than two hours of “entertainment” screen time a day. The goal was to curb risks associated with heavy media use, among them disrupted sleep, online safety, cyberbullying and physical inactivity.

    Originally created for young people’s engagement with stationary media that tend to be confined to one room or context – for example, watching television – these hourly limits became outdated with the integration of smartphones and other digital devices into everyday life. Compared with watching television, online media was far more difficult to track and define, and more nuanced in its use.

    Developmentally beneficial activities such as educationsocializing and leisure have come to rely on the internet to extend and maintain face-to-face connections. Remote schooling and social distancing during the COVID-19 pandemic only accelerated this digitization of daily life.

    In my view, adopting strict time limits and restrictions could pose risks to children’s well-beingautonomy and development, for example, by harming adolescent self-esteem.

    The latest guidelines

    In January 2026, the American Academy of Pediatrics retired its decade-old framework that had largely organized its advice around hourly screen limits. The new policy statement on children, adolescents and digital media diverges from this blanket approach. Instead, it suggests parents consider the larger picture in which this media use exists rather than lumping all screen use together.

    Similar to the World Health Organization’s 2019 guidance for children under 5, the American Academy of Pediatrics still advises that parents avoid screen media for children younger than 18 months. This recommendation is largely because extended use by children by themselves can be problematic for many young children, crowding out important developmental milestones.

    Both the World Health Organization and the American Academy of Pediatrics also recommend that when children under 24 months use screens, they should be limited to content and devices that encourage children and caregivers to interact. For ages 2 to 5, screen time – including TV and interactive apps on devices – may be extended to more solo use, provided it’s high-quality digital media designed around learning goals in mathematics and reading. But recreational use should be limited to roughly an hour per day.

    For school-age children and teens, the newest guidance has begun to step away from fixed screen time limits and asks families to weigh online activity in the context of everyday life.

    Doing so recognizes that a child’s digital experiences are shaped by diverse factors rather than the hours spent online. Current guidelines call on caregivers to distinguish among types of media, from television and social media to video games and interacting with artificial intelligence chatbots. They also call for taking into account a child’s individual characteristics, such as their interests and personality, family members’ own use of screens, and the type of content children are spending time on.

    Rethinking screen time

    Moving beyond strict screen time limits includes questioning the kind of digital activities kids and adolescents participate in. Do the activities encourage time spent interacting with others online, which can help young people develop important skills and competencies?

    Scrolling an algorithm-based, auto-playing video feed likely does not equate to the same opportunities as video-chatting with friends, creating digital art or working with teammates in a multiplayer game. Research suggests these different uses relate to development in different ways and can help kids develop varying skill sets pertaining to everyday life and schooling.

    Indeed, a large review of current research found that young people who take part in a range of digital activities, such as browsing the web, online gaming or interacting on social media, show positive associations with social connection, identity exploration, civic participation and learning.

    A woman and two small children look at tablet screen
    Parental involvement in young children’s screen time has developmental benefits. Cultura Creative/Tetra images via Getty Images

    Using these guidelines at home

    The current evidence suggests parents and caregivers are best positioned to be digital instructors. Cutting children off altogether can carry its own risks for social and emotional development. Caregiver mediation of children’s screen time can produce widely different outcomes and effects, depending on whether the guidance is supportive or controlling.

    Considering your own digital media use is the first step: Are family members engaging in problematic or heavy media use that children in the household might emulate? What applications and uses are most common in the family, and what positive or negative effects might they have, depending on the child’s age? How could these digital activities be safely integrated with other everyday experiences to increase their benefit for children? Conversely, what online time might be better spent on face-to-face experiences?

    The American Academy of Pediatrics’ Family Media Plan tool turns these ideas into concrete questions. For example, it recommends working out what each child needs from digital technology, what activities screens might be crowding out, and where their family or household can build in screen-free time. The recommendation is to talk with each child about why they are drawn to particular apps or online activities, what they encounter while browsing, and what might be lost when kids bring phones to gatherings such as mealtimes.

    The debate over young people’s screen time is not going away. But the most up-to-date guidelines, and the growing body of research behind them, make a strong case for a more holistic approach. The guidelines treat digital media as a complex, diverse and evolving environment that children need to learn to navigate in the digital age. The risks and rewards depend, as with any developmental setting, on the child, the content and what online time might be crowding out.

    This article originally appeared on The Conversation. You can read it here.

  • ER doctor and mom sets the record straight for parents of kids with e-bikes and e-scooters
    Photo credit: CanvaA boy rides an e-scooter, left, while a girl is examined in an emergency room.

    An emergency room doctor and fellow mom has been noticing a troubling trend: Many parents are giving their kids something more powerful than bicycles to get around the neighborhood. As a result, she’s seeing more children come into the ER with injuries sustained in e-bike and e-scooter crashes. She recently went online with a plea to parents and young riders.

    Dr. Meghan Elizabeth Beach Martin, known online as Dr. Beachgem, posted a video in her scrubs discussing her concerns after seeing so many children come into the hospital with e-bike injuries during the summer months. She’s worried that too many kids and parents don’t understand the proper safety precautions. As a mother herself, she even questions why children are allowed to ride these devices at all.

    In the video, the doctor explains that some e-bikes can reach speeds of up to 28 mph. She says that if an e-bike goes any faster than that, it’s technically classified as a motorcycle. At those speeds, she regularly sees children with traumatic injuries and broken bones after hitting bumps, cracks in the road, or other vehicles. Many of them aren’t wearing helmets or protective pads, and some are even riding barefoot, making their injuries even more severe. Martin’s video has gained traction on Reddit and elsewhere online.

    E-bikes and e-scooters, examined

    Martin isn’t the only professional seeing a growing problem. The American College of Surgeons reports that there are more than 20,000 e-bike-related injuries each year. Meanwhile, a University of California, San Francisco study found that e-bike injuries doubled annually from 2017 to 2022. The same study found that e-scooter injuries increased by 45% each year during the same period.

    Before riding an e-bike, it’s important to follow proper safety procedures. Make sure you and your child understand your area’s laws regarding e-bikes, including any minimum age requirements. Always wear a helmet and other protective gear when riding. Consider choosing an e-bike with safety features such as motor-interrupt brake levers and disc brakes. These are just a few of the many safety tips experts recommend.

    The U.S. Consumer Product Safety Commission has similar safety tips for e-scooter riders. Wearing a helmet is one of its top recommendations, along with taking other basic precautions. The agency also recommends checking the brakes before riding and slowing down for bumps, cracks, and other road hazards.

    The vast majority of e-scooters and e-bikes are designed for only one rider, so avoid doubling up. Although laws vary by state and locality, wearing more protective gear is always the safer choice. Riders should also review local e-bike and e-scooter laws to make sure they are operating the vehicles safely and legally.

    A little research goes a long way toward making sure you and your children can ride safely. It’s also important for parents to understand that many e-bikes and e-scooters can travel at speeds that make them very different from a traditional bicycle. The last thing you want is for you or your child to become another emergency room statistic.

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