Photo credit: Cover Image Source: Boji, an Istanbul street dog rides a subway train on October 21, 2021 in Istanbul, Turkey. (Photo by Chris McGrath/Getty Images) – Array
Each year, millions of tourists flock to Istanbul, Turkey’s largest city, drawn by its grand palaces, elegant timber mansions, lush parks, scenic ferry rides, and intricate ceramic art. But among the bustling crowds and historic sites, visitors may notice an unusual local celebrity—the friendly face of Boji, a commuter street dog known to just about everyone who regularly travels through the city.
Image Source: Boji is a regular Istanbul commuter, using the city's public transport systems to get around, sometimes traveling up to 30 kilometers a day using subway trains, ferries, buses and Istanbuls historic trams. (Photo by Chris McGrath/Getty Images)
Boji, once a stray, has become a dedicated commuter, exploring Istanbul via ferries, buses, metro trains, trams, and subway cars. His name, “Boji,” is derived from the Turkish word for “bogie,” the area between subway cars he loves to ride. This Anatolian shepherd mix, with his golden-brown coat, soulful dark eyes, and floppy ears, has won hearts across social media, achieving near-celebrity status as the city’s most beloved passenger.
Image Source: Boji has learnt how and where to get on and off the trains and ferries. As people began to notice him as a regular on their daily travel routes and since the tracking app began, Boji's travels have made him an internet sensation. (Photo by Chris McGrath/Getty Images)
In 2021, municipal officials were amazed to learn about this dog’s travels. They arranged for his vaccination and fitted a microchip on his body to track his movements. The trackers reported that Boji traveled an estimated 30 kilometers a day, passing through dozens of metro stations and taking at least two ferry rides. “He knows where to go. He knows where to get out,” said Aylin Erol, the head of customer relations at Metro Istanbul, per CNN.
Image Source: Most days, Boji will pass through at least 29 metro stations and take at least two ferry rides. (Photo by Chris McGrath/Getty Images)
Later that year, Chris McGrath, a Getty Images photographer, spent a day with Boji and documented his adventures in a series of photographs. In his interview with CNN, McGrath described the canine as a ” free spirit. All he wants to do is ride on transportation. Every time he goes past a bus or van, or any form of transport, he just wants to get on it. It’s quite bizarre.”
Image Source: Since noticing the dogs movements the Istanbul Municipality officials began tracking his commutes via a microchip and a phone app. (Photo by Chris McGrath/Getty Images)
McGrath recalled that Boji is well aware of what he needs to do and where he needs to go while traveling on trains or ferries. He also said that Boji likes the vibrations of the vehicles’ engines, so he usually sits where the wheels are underneath. The pup doesn’t like cats, though.
Image Source: Getty Images | Photo by Chris McGrath/Getty Images
Although nowadays, Boji has a Wikipedia page dedicated to his information, McGrath first learned about him via Twitter, “Everybody knows him now. Everybody sees him,” he said. McGrath described that municipal officials also took Boji for grooming and behavioral therapy sessions, gave him some TLC, and created a kennel at one of the metro stations.
Image Source: Getty Images | Photo by Chris McGrath/Getty Images
McGrath also said that the municipality will soon be putting posters of Boji on the transit system, guiding people on how to interact with him. “He doesn’t listen to anybody. Like if you do try to tell him something, he just ignores you. Lots of people say, ‘Come over here, sit here,’ and he just ignores it. He goes where he wants to go. He’s that sort of spirit. He just wants to go and do his own thing, and travel around, and he’s quite content doing it.”
Image Source: Getty Images | Photo by Chris McGrath/Getty Images
In 2022, according to the Daily Sabah, Boji was adopted by Mehmet Ömer Koç, a billionaire, Turkish businessman, art collector, and chairman of Koç Holding. At this time, the commuter dog was spending his days at a shelter operated by Istanbul Metropolitan Municipality (IBB) to stay warm in the cold weather. That’s when the city’s mayor, Ekrem Imamoğlu announced his new home on Twitter and thanked Koç, “Boji, Istanbul’s world-famous dog, now has a home where he can roam, run freely. He will be away from people who wanted to hurt him,” he tweeted.
Boji’nin artık rahatlıkla dolaşabileceği, özgürce koşabileceği bir yuvası var.
İstanbul’un dünyaca meşhur köpeği Boji’yi sahiplenen iş insanı Ömer Koç’a teşekkürler. Boji’nin, ona zarar vermek isteyen insanlardan uzak, korunaklı, dilediği gibi koşturabileceği bir yuvası olacak. pic.twitter.com/ERjUJXcJ5V— Ekrem İmamoğlu (@ekrem_imamoglu) January 11, 2022
According to Hurriyet News, in 2022, Istanbul’s celebrity pooch also inspired a cryptocurrency project aimed at helping stray animals. A portion of the transaction fees obtained from the cryptocurrency released under the name “Boji Token” is donated to shelters as dog food.
Wanderlust can take one to places, and in the case of Boji, he is already on his way to traverse the globe. According to his Wikipedia page, Boji was last spotted in London with his owner on a London bus. Well, he is the dog who likes to wander and wouldn’t stop!
Paying college students about US$5 a night to sleep seven hours got them a quarter more nights of adequate sleep – and better grades.
That is what we found in a study we published in July 2026.
We gave more than 1,100 undergraduates at University of Pittsburgh a Fitbit – a wearable activity tracker that looks similar to a watch – and an app that sent bedtime reminders and morning feedback. We randomly chose 468 students and paid them about $5 for every night they slept at least seven hours, over the course of four weeks. We verified how much they slept using the device they wore.
The students were about 19 years old, on average, and half of them were first-year students. Roughly 72% of them were women. About 55% were white, 28% Asian, 9% Black and 4% Hispanic.
Our study shows that offering an immediate financial reward can help students meet a seven-hour sleep goal, and that those effects can persist up to a month beyond when the students are paid.
Half were going to bed after 1 a.m. on average – a quarter after 2 a.m.
Students got the recommended seven hours of sleep on a typical weeknight on only 43% of their nights, and more than 85% fell short at least once a week.
They also did not know how much sleep they were getting. Two-thirds told us they usually slept seven hours – the trackers showed only about one-third of students slept that much on even three nights out of five.
And 94% said their ideal night of sleep was longer than the one they were getting.
What the money bought
The 468 students we offered nightly payments reached seven hours of sleep on 26% more nights than 380 students who were not offered the money. That is a large shift for a group in which fewer than half were hitting the mark to begin with.
Students receiving the monetary incentive slept 19 more minutes per school night, roughly the difference between closing the laptop at 11:40 p.m. or at midnight.
Among students receiving the payment incentive, their GPA rose by about 0.08 points that semester – roughly a quarter of the gap between students who arrived with above-average and below-average high school grades.
Once the payments stopped after four weeks, students who had received the money were still sleeping about eight minutes longer per night for the remaining three to four weeks of the study. The effect was smaller than during our study, but our findings suggest that some of the change in sleep habits persisted for up to a month after the end of the incentive.
The effects of the intervention on sleep and GPA were largest among first-term freshmen, whose routines are not yet necessarily fixed.
Rewards work – if they come right away
Timing mattered too: Delivering the payment as a lump sum at the end of the semester, rather than every morning, produced only about two-thirds of the effect on sleep.
The effects of the intervention on GPA faded over a couple of academic terms. Grades remained higher in the following semester, but two semesters later we could no longer detect an effect.
Bedtime reminders and morning feedback on their own – with no money attached – had little effect. Students who received them slept only marginally more. The problem was not motivation: Nearly all said they wanted more sleep than they were getting. The challenge was following through on that intention night after night.
Investing in sleep
Our results show that universities should look at how the environment they create fosters or discourages good sleep habits.
Late evening deadlines to submit assignments and early classes can both make it harder for students to get enough sleep. Changing some of these features costs little compared with many academic support programs, and it may be worth testing alongside other interventions aimed directly at students.
Reminders and feedback might also work better if they change over time, rather than becoming familiar and easy to tune out.
Very few universities or students treat sleep as part of an investment in education, or ask whether the schedules and incentives schools create make adequate sleep harder. Our results suggest they should.
If you grew up in the United States in the 1980s or ’90s, chances are you remember The Oregon Trail. For many like me, it was our first computer game and our first introduction to wilderness survival. We hunted buffalo, forded rivers, broke wagon wheels and, of course, learned about dysentery years before Google even existed, all while hoping our group would make it to Oregon City alive.
Lately, the game has found a second life. Nostalgic social media posts, memes and updated versions of the game have introduced The Oregon Trail to a new generation while reminding millennials just how unforgiving that grainy computer screen journey could be.
As a physician who specializes in emergency and wilderness medicine, I started thinking about how much of what the game taught me about surviving in the wilderness still applies today. After all, modern hikers and campers have access to tools the pioneers could never have imagined.
Surprisingly, I’d argue that more lessons from The Oregon Trail hold up than you might think.
Clean water is crucial
The Oregon Trail game made dysentery famous for an entire generation. Fortunately, advances in sanitation, hand hygiene and antibiotics have made large outbreaks like those that wagon trains and military camps experienced much less common, at least in the United States.
That doesn’t mean gastrointestinal illnesses have disappeared. Traveler’s diarrhea and cholera are still an important cause of illness around the world. Untreated water, poor hand hygiene and contaminated food can still derail any trip.
Simple habits such as purifying drinking water, washing hands before meals and after using the bathroom, and practicinggood camp hygiene remain some of the easiest ways to stay healthy outdoors.
Water purification is important with wilderness travel in the United States and in many areas of the world. There are many easy and cost-effective ways to purify water, such as boiling, filtration and treating with chemical disinfectants. Each method has its benefits and downsides.
Boiling is often the most accessible method. While it can kill bacteria, viruses and parasites, it will not remove water contaminants such as heavy metals, including lead and arsenic, or industrial contamination such as pesticides. Consider boiling your water for at least one to three minutes, depending on your altitude, to purify it. Water filtration is an easy option for backpackers but is less effective at removing viruses.
You may no longer have to ford the river with oxen, but rivers, lakes and other bodies of water present unique hazards that outdoor adventure enthusiasts can overlook.
Moving water can be more dangerous than people realize. Even the best swimmers can drown in rip currents.
Cross bodies of water only when absolutely necessary. Avoid any water crossings after recent rainfall, as the water level often rises and the current can be faster and stronger. Submerged objects – rocks, fallen trees and other debris – as well as changing weather, flash flooding and strong currents can make crossing more dangerous.
It’s not just a broken wagon axle that can send a trip sideways. One thing The Oregon Trail captured well is how distancechanges everything. A sprained ankle in a city usually means an inconvenient trip home or to the doctor, but a sprained ankle 5 miles from the trailhead may mean that someone will need to carry you. The same is true for other common wilderness concerns, such as dehydration, heat illness, infections or even blisters.
Preparation is about packing a first aid kit and thinking ahead. Ask yourself what you would do if your hike took twice as long as expected or if you unexpectedly had to spend the night outside. Research your route and carry more food and water than you think you’ll need. Check the weather and be prepared for it to change, with extra clothing and options for rain.
No one tackled the Oregon Trail alone because it meant you would not survive. There is a lesson here in solo travel and solo mountaineering.
Traveling alone means that a minor injury such as a sprained ankle could mean crawling to the trailhead to call for help or waiting until you are identified as missing. If you cannot find someone to travel with you, provide an itinerary and travel location to a trusted person. Make sure they know when you should be returning and plan to check in. If you do not return as expected, they can call for help.
Respect the wildlife
Large animals still pose a threat across the country. While there may be fewer bison than previously seen on the Oregon Trail, animals in nature deserve respect.
No selfie is worth being attacked by a brown bear. If you see a dangerous wild animal, avoid approaching and immediately leave the area.
Venomous snakes are present throughout much of the United States and continue to cause significant injury and death around the world. If someone is bitten, please don’t try to cut the wound or suck out the venom. Instead, keep the person calm, minimize unnecessary movement, and focus on getting them to professional medical care. Antivenom is available in many major hospitals in the United States.
Even smaller and more docile animals such as deer and squirrels should not be fed. It is dangerous for an animal to get used to receiving food from humans. Additionally, animals carry diseases, such as rabies and leptospirosis, that can be fatal to people.
Don’t attempt to get close to any animals, no matter how calm or asleep the animal appears to be.
Technology is a backup, not a plan
One of the biggest differences between today’s outdoor adventures and those of the Oregon Trail is the ability to communicate.
Cellphones, GPS apps and emergency beacons have made it possible to call for help from places that were once completely isolated. However, while those devices are incredibly valuable, they shouldn’t encourage you to take bigger risks, as help may be far away, slow to arrive, and injuries in the wilderness can be fatal.
Travelers can use a smartphone with GPS capacity to avoid getting lost, but downloading any needed maps for offline use can help prevent lack of service from derailing your trip.
Additionally, an unlocked smartphone that isn’t restricted to one carrier is a great way to store and communicate critical data, such as travel plans and copies of your medical history.
The Oregon Trail travelers worried about river crossings, disease and harsh weather. Today’s hikers face different challenges depending on where they are.
Desert hikers may struggle with extreme heat and dehydration. Mountain travelers face rapidly changing weather, lightning and high altitude. And coastal explorers can face problems such as riptides, waves, cliffs and unexpected rocky surfaces.
Altitude illness is often unpredictable and can sneak up on you. Most people experience acute mountain sickness within 24 hours of ascent, developing symptoms such as headache, fatigue, nausea or problems with sleep. Any confusion, difficulty walking, shortness of breath or coughing up significant phlegm should prompt an immediate descent.
There are commonly used prescription medications to help prevent and treat altitude illness. The mountain will always be waiting for your next attempt.
Some lessons survive every software update
Part of what made The Oregon Trail game memorable is that every decision mattered. Success often depended less on luck than on planning ahead, and that lesson still applies.
When people ask me what one emergency medicine skill everyone should know before heading outdoors, my answer is usually preparation. Thoughtful planning prevents far more emergencies than any single piece of equipment.
For people who spend a lot of time outdoors, I also recommend taking a wilderness first aid course. These courses teach practical skills to provide medical care in a wilderness environment.
Nature is no less powerful or unforgiving than it was on the Oregon Trail, and treating it with respect is essential. Combining advances in modern medicine with thoughtful preparation helps stack the odds in your favor so that, just as every Oregon Trail player hoped, everyone in the party makes it to the end.
Have you ever taken months off training – maybe due to an injury, a new baby or crushing work deadlines – and come back convinced you were starting from zero?
Research from our team has some good news: At the cellular level, you probably weren’t.
We found that muscle and liver cells store memories fromevery training session in ways that may help improve endurance, control blood sugar levels and even slow weight regain after inactivity.
Use it or lose it? Maybe not
For most of the past century, long before fad diets and fancy workout trends took off, exercise was considered one of the most effective lifestyle changes to lower the risk of heart disease, Type 2 diabetes, several cancers and early death for people of all ages. But people typically understood exercise as something whose beneficial effects fade away over time: You use it or lose it.
When you stop training, your maximum oxygen uptake, muscle gains and insulin sensitivity drift back to where they started, often within weeks. Physical activity guidelines are built on this fact, which is why they emphasize consistency above all else.
Consistency, however, is a luxury that roughly 3 in 4 American adults aren’t able to enjoy. People can experience injuries, illness, pregnancy or jobs that limit their time for or ability to exercise. If adaptation really resets, every time you step into the gym would be as if you’ve never been there before. But that scenario doesn’t match what coaches and returning athletes typically describe: In practice, people who have trained before can get fit again faster than those who haven’t undergone similar training.
In recent years, however, scientists have started challenging the concept of “use it or lose it.” New research hints that your cells might keep a record of your training history so all of your gains are not completely lost.
More than muscle
We areexercise physiologists who study how cells remember exercise. Our lab and others have shown that the body is able to store a form of exercise memory across different organs.
To study how this exercise memory works, our team of researchers use an ON-OFF-ON exercise training protocol in mice, which involves an initial four- to eight-week training period, followed by detraining – a period of no exercise – and a second training bout. This method allows us to examine how cells form a memory of exercise, maintain a record of exercise through detraining, and recall memories of prior training when exposed again to exercise.
Using this strategy, our team found that skeletal muscle memory accelerates muscle growth. Compared to mice with no training history, mice who retrained grew bigger muscles, and the individual muscle fibers inside those muscles grew too. Larger muscle fibers meant that the working cells were themselves getting bigger, rather than the surrounding tissue.
Looking more closely at these muscle cells, we found that retrained muscle is better at matching energy production to demand – meaning, the muscles were better at drawing from energy stores when it’s needed most – and this ability persists without further exercise. This memory held even when the mice ate a high-fat diet, suggesting that prior training can still offer benefits even when diet is working against those gains.
Muscle isn’t the only body part that learns from exercise. Working muscle needs fuel, and the liver supplies it during and after training sessions.
My colleagues and I found that liver cells also store exercise memory and uses it to feed muscle more efficiently. In both mice and people who trained, stopped, then trained again, their livers released higher levels of a family of enzymes called carboxylesterases. These enzymes chop up lipids circulating in the blood, delivering fat in a form that muscle can take up and burn as it grows.
A record that outlives you
Recorded cellular memories of exercise may even be passed down to future generations.
In mice, we found that three to four weeks of maternal and paternal endurance exercise can have a lasting effect on their offspring. Compared to offspring born to sedentary parents, parental exercise granted protection against poor blood sugar levels and excess weight gain for an entire year after birth.
But there remains much to be discovered on how parents influence the health of their children and whether their lifestyle could provide a fitness advantage across generations.
Every cell remembers
Biology has traditionally granted memory to a short list of cells. Neurons store memory in the connections between them. Immune cells store memory so they can recognize pathogens faster and more strongly the next time they encounter them.
Researchers previously considered all other cells to be memoryless; a cell responds to a signal, then returns to baseline without keeping a record of that interaction. But that assumption is now coming apart.
Skin stem cells can keep a record of inflammation, allowing them to heal a new wound faster months later. Human fat cells keep a record of obesity that persists even after substantial weight loss, which may account for why you gain weight faster when switching back to a high-calorie diet – the so-called yo-yo effect.
We propose that every cell in the body remembers exercise, regardless of how little or how much someone trains. The question is how long these records are stored and whether researchers could prolong or expand each cell’s storage capacity. Better understanding of how cells learn and remember exercise, where they store memories and how those memories are preserved could help improve exercise guidelines for those who cannot exercise for prolonged or consistent periods of time.
To be clear, none of these findings are evidence for skipping the gym; nothing in our data suggests the effects of past training can substitute for present training. But there is hope that the work you put into getting in shape isn’t completely lost over time.
Somewhere, deep in your cells, there is a record waiting to be replayed the next time you lace up your running shoes, pick up a pair of dumbbells or want to fulfill a New Year’s resolution.
