If you’ve ever played “Cards Against Humanity,” then you know the drill: the key to victory is personalizing your jokes to get your friends crying from laughter. But what if we flipped the script on our typical Friday night activity and made it about sharing our feelings and addressing mental health instead?


That’s Stuart Fitzwilliam’s idea, and it could change the way we think about dealing with anxiety. Cards for Calm is a game designed to help people address negative behavior patterns both on their own and in the company of friends and family. GOOD had the chance to talk to Fitzwilliam about his new product, which is currently available for pre-order on Kickstarter.

What gave you the idea to create this card game and start a crowdfunding campaign to support it?

The whole thing sprang out of my own experience. Almost exactly two years ago this month, I began treatment for depression. I [have been] in remission for over a year and a half now and all of the techniques that essentially went into the cards are various things I learned in therapy and things I’ve used since recovery to help me stay on track. One of the issues is always that little active negativity and habits can sometimes spiral… leading to relapse. So these are all things I use just to manage my own symptoms.

[quote position=”left” is_quote=”true”]I wanted to come up with a way that would help people think about these things and help them deal with their own personal issues and anxieties[/quote]

One of the real things I’ve found, especially before I found treatment, was that people don’t tend to talk about things like depression. Especially if you look specifically at the male demographic, we’re traditionally encouraged to not talk about our feelings. So I wanted to come up with a way that would help people think about these things and help them deal with their own personal issues and anxieties. But also try and find a way to let them either deal with it themselves or sit down with friends and create an environment where people would feel safe sharing little things that they wanted to work on about themselves. And that’s really where the idea of the card game sprang from.

How does it work and how do you use them?

There’s two variances of it for the one deck. So there’s a single player version and you can use that on a daily basis. The best way I’ve found to start is to shuffle the deck at night right before you go to sleep, and put the deck on top of the screen of your phone. Because we all wake up in the morning and the first thing we do is reach for our phones. I’m as guilty of that as anyone. It’s not the healthiest habit, so that way, putting it on the screen gives you the option of ‘oh, maybe I’ll take a card or maybe I’ll take a minute to myself to think about what I want to do today.’

The idea is that in the single player version, you can play however many times you want to in a day. It’s almost like a solitaire type of game I suppose where you keep track of the score—just of the number of cards you play—per day… It is a really good way of tracking how many times a day you’re creating these moments for yourself.

So, just to break it down, when you actually play a card, the deck is split into two. So there are behavior cards and action cards… Each behavior card has a corresponding action card, and the action card helps you think through your situation a little more and helps you think of creative ways to try and resolve it. And those ways can be either real-world actions you can take to try and resolve that or creative visualizations that help you reframe the situation.

What’s the benefit to making it a game and not another self-help book?

[Self-help books] work really well, but they tend to be things that I read once and I think, ‘That’s really good,’ and then put it back on the shelf or back beside the bed. And then I never quite remember to pick it back up, because if something’s 200 pages, it’s not always easy to jump in and grab the one thing that you want… But a deck of cards is the kind of thing you can carry with you easily. It’s a much more accessible format and the kind of thing where people can… flip over a card and read that while waiting for a coffee at Starbucks.

According to Newsweek, 1 in 5 Americans suffer from mental health problems in some capacity each year. Why do you think people still have hang-ups talking about mental health when it’s something many of us experience?

I mean, certainly the stigma around mental health is decreasing and people are getting generally a broader understanding that caring for your mental health is not dissimilar to caring for your physical health. But there is still so much overt and covert social pressure on men in particular that thinking about feelings isn’t something you do. There’s the phrase you hear a lot that you should just ‘man up,’ and it’s implicit that trying to deal with these things is in some way the antithesis of what you should be doing as a man. And those stigmas are beginning to slide, but they’re kind of endemic in our culture and I don’t see them going away for a few generations yet.

[quote position=”right” is_quote=”true”]there is still so much overt and covert social pressure on men in particular that thinking about feelings isn’t something you do[/quote]

In an attempt to change that negative aspect of our culture, would you encourage people to play the deck with other people?

There is a multi-player version, which is kind of like “Cards Against Anxiety”… In that scenario, each person takes turns controlling the deck… They read the behavior card along with the corresponding action card and, along with the other players, explain as much as they’re comfortable the problem they have. Each of the other players takes a turn trying to think of some kind of creative way they can deal with this… When each player’s made a suggestion, whoever’s controlling the deck awards the card to the player they feel made the suggestion that was most helpful to them… With the multi-player version, the way you win is by offering as much help to your friends as you can.

I think a game scenario is really something where people will sit down and talk about these things. It can be relatively minor or it can be something more deep and personal… but it’s a great way for people to begin to explore talking about their feelings.

At the very least, it’s nice to think of doing something with your friends and family that doesn’t revolve around screens. Do you have any other suggestions for people who are trying to disconnect more often to give themselves a mental break?

Sometimes it’s as simple as putting the phone in the other room, or if I’m at home, just pulling the power cord out for the Wi-Fi. I like that you have to physically make an effort to reconnect everything… I use Trello quite extensively just to manage everything going on in my life, and I found it really helpful when I made a self-care Trello board, which was just a list of six or eight tasks to do daily. And the goal was never to do each of them daily. If I could move over at least half of these cards each day from “to do” to “done” then I know I’ve made a reasonable amount of time for myself. And they’re things like doing yoga, going for a run, reading, sitting outside—things that are obvious that sometimes we miss. Just that simple little list… I found really beneficial.

  • Scientists find that Japanese frog gut bacteria destroys cancer tumors in a single treatment
    Photo credit: CanvaNew hope against colorectal cancer comes from Japanese tree frogs.
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    Scientists find that Japanese frog gut bacteria destroys cancer tumors in a single treatment

    New hope against cancer comes from the intestines of tree frogs.

    A new remarkable finding could help the fight against cancer. Researchers in Japan have found specialized bacteria that not only wiped out cancerous tumors in mice, but did so in one single treatment. The kicker is that this tumor-busting bacteria was found within the guts of Japanese tree frogs.

    Professor Eijiro Miyako and his team at Japan’s Advanced Institute of Science and Technology (JAIST) were looking for direct methods to use natural bacteria strains to attack cancer cells. They collected and isolated 45 bacterial strains from the intestines of Japanese tree frogs, fire belly newts, and grass lizards. They then proceeded to test each one on cancerous tumors found in lab mice.

    The research

    After experimentation and systematic screening of the 45 bacterial strains, nine of them showed anti-tumor effects. However, the E. americana strain found in Japanese tree frogs showed the highest potential. It didn’t just kill the cancer cells in the mice, but engaged the immune system within the mice to “comprehensive tumor destruction.” 

    Within a single dose of E. americana, mice with colorectal cancer had a 100% response rate that led to complete elimination of all tumors. This breakthrough surpasses the response of current standard therapies to treat this type of cancer, including chemotherapy agents.

    Is this bacteria safe?

    The E. americana strain also showed an excellent safety profile. Aside from mild inflammation responses that usually normalized within 72 hours, there appears to be little negative effect. There was no bacterial colonization detected in the organs of the mice. There was also no chronic toxicity during 60 days of extended observation. While more and extensive testing is needed to confirm, this colorectal cancer treatment appears to be effective, quick-acting, and safe.

    Great news during a trying time regarding colorectal cancer

    This news comes at a time when there has been a rise of colorectal cancer rates among younger people. In fact, it’s the most common cancer-related death among people under 50 years old, and second most common cancer death overall. This tree frog bacteria could significantly impact those statistics. If the potential rings true, a single dose could eliminate all of the tumors without the need of surgery.

    The researchers intend on testing this bacteria on other forms of cancerous tumors. They also want to test other, safer administration methods to see if it can be even more effective. While it can already help eliminate colorectal cancer tumors, testing might show it to be an effective overall cancer treatment.

    Reptile and amphibian research helps human medicine

    While humans are biologically different from reptiles in numerous ways, many medicines have been derived from them. GLP-1 drugs such as Wegovy and Ozempic were created after discovering that gila monster venom reduced blood sugar. Similarly, snake venom has shown signs of being effective in reducing pain and inflammation as an arthritis treatment. It’s not just gut bacteria, but venom from all sorts of reptiles and amphibians is being tested as cancer treatments, too.

    Whether you’re a fan or not, reptiles and amphibians could hold the potential to save thousands of human lives.

  • Nearly 20% of new moms have anxiety or depression, but a promising psychedelic treatment is on the horizon
    Photo credit: Justin Paget/DigitalVision via Getty ImagesWomen with postpartum depression and anxiety have a higher risk of birth complications and death by suicide.

    About 1 in 5 women will experience depression and anxiety during pregnancy or in the year after giving birth. If untreated, a mother who has these conditions has a higher risk of birth complications, overall poorer health, impaired bonding and nurturing of her infant, and a higher risk of death by suicide.

    But a new treatment moving through the Food and Drug Administration clinical trials process may be key to treating, or even curing, depression and anxiety in postpartum people. It is a newly named psychedelic, luvesilocin. It functions like psilocin, the psychoactive chemical within psilocybin mushrooms. It may be able to positively affect the unique hormonal shifts, brain changes and disconnection that can lead to these conditions like no existing treatments.

    In prior studies of psilocybin, researchers have observed rapid improvement in symptoms – and sometimes a cure after a single dose – of conditions such as major depression and PTSD. In a recent FDA Phase 2 study of luvesilocin, we found similar improvements in postpartum depression.

    I was the site investigator for the University of Colorado, one of 35 participating sites across the U.S. The study enrolled 84 postpartum women who were within a year of giving birth and ended in May 2025.

    I have spent my career as a board-certified obstetrician-gynecologist contemplating how the prenatal experience shapes lifetime health. I have also followed the psychedelic data closely. I’ve been eager to find evidence-based pregnancy and postpartum applications of psychedelics, given these drugs’ promise in treating other mental health conditions.

    Depression and anxiety’s impact on moms and babies

    One drug that has been studied and enhanced our understanding of the way psychedelics work is MDMA, which is commonly known as ecstasy and causes a euphoric high.

    According to peer-reviewed research published by Bessel van der Kolk in 2024, MDMA can lead to improvements in individuals being able to identify, describe and feel their feelings. Other improvements resulting from MDMA assisted therapy include more self-compassion and a broader desire and capacity for connection with others.

    Connection, especially the earliest one between a mother and infant, plays one of the most significant roles in providing the foundation for humans to grow and flourish. Postpartum depression is often defined by disconnection and impaired bonding.

    Children born to mothers with untreated depression and anxiety have a higher risk of falling behind on early developmental milestones. They may also have behavioral concerns, such as hyperactivity or ADHD, and are more likely to withdraw from social activities. They tend to report somatic complaints, such as body aches and pains in early childhood.

    Children of mothers who had depression or anxiety during pregnancy are also at risk of these same conditions as they enter their teenage years. They have nearly twice the risk of these conditions compared to teenagers whose mothers did not have untreated depression and anxiety. This pattern means depression and anxiety can become a multigenerational cycle. But this cycle can be interrupted with adequate treatment and support.

    Increased levels of the hormone oxytocin were found by researchers in the blood of depression study participants who were given MDMA, LSD and mescaline, which are all psychedelic drugs. The increase in oxytocin led to more feelings of trust, empathy and connection.

    Oxytocin is a hormone produced in the part of the brain called the hypothalamus and is released from the pituitary gland into the bloodstream. It plays a critical role in birth and infant feeding. It also aids in the wiring and formation of human social brains.

    Oxytocin is important in maternal bonding with an infant. Conversely, early childhood stressors, such as a mother suffering from mental illness, reduces oxytocin levels in children. This may be a contributor to adverse mental and physical health outcomes later in life.

    In depression studies that involved men, psilocybin did not have as great of an impact as other psychedelic medications on oxytocin production. But there is reason to believe that oxytocin may play a greater role in postpartum patients because it’s levels are higher during birth and lactation than in other phases of life.

    FDA study of psilocybin-like medication

    In February 2026, the FDA granted luvesilocin breakthrough therapy status. This status is used to speed up the development of promising new medications for serious or life-threatening conditions. The drug received this status because our research found meaningful and rapid reductions in depression scores in those who received the treatment.

    In the Phase 2 study, 77% of postpartum women who received a psychedelic dose, 30mg of luvesilocin, had significant improvement in their postpartum depression. Overall, 71% had no symptoms of postpartum depression seven days after the psychedelic session.

    The purpose of an FDA Phase 2 study is to determine the effectiveness of an experimental medication on a particular disease or condition. In this case, the study is evaluating luvesilocin’s effect on postpartum depression scores and symptoms. In the group that received the placebo, a microdose of the drug, more than half experienced an improvement in their symptoms, but most still had some symptoms after seven days.

    These are much higher response and remission rates than trials of the existing medications used for postpartum depression treatment. Existing treatments include selective serotonin reuptake inhibitors, known as SSRIs, and a medication called zuranolone. The latter is the only medication to have specific FDA approval for postpartum depression.

    Access to psychedelic treatments

    In 2023, the Colorado legislature passed the Natural Medicine Health Act. It offers a legal pathway for people to receive natural psychedelics, such as psilocybin mushrooms, in therapeutic settings. The first natural medicine healing centers opened in early 2026. Some locations advertise treatments for everything from postpartum depression to birth trauma.

    Oregon has a similar state-regulated program. Numerous other states have different pathways toward legal psychedelic-assisted therapies and decriminalization of psilocybin-assisted therapy. Nationally, there was a recent federal executive order to accelerate action on treating serious mental illnesses. The order included mention of the use of psychedelic therapies.

    Looking forward

    By the end of 2026, Phase 3 of the luvesilocin trial for postpartum depression is slated to begin. Phase 3 trials are conducted to confirm the effectiveness and further evaluate the overall risks and benefits of a new medication. Each phase is an important regulatory step before a medication can be approved and available in clinical settings.

    In Phase 3, 200 participants with postpartum depression will be recruited across participating sites. While I’m optimistic about the potential of this research, I believe its value can be established only through rigorous blinded clinical trials, objective data analysis, and conclusions and approval that are fully supported by the evidence.

    Phase 3 will also include participants who are still breastfeeding. A study of luvesilocin during lactation in healthy volunteers demonstrated very low levels passed from the mother into breast milk. Thus, this medication would be considered safe for breastfeeding.

    Luvesilocin may become a game-changing postpartum depression treatment medication in just a couple more years. On a much larger scale, psychedelic medicine could elevate our collective well-being and happiness, replacing systemic cycles of depression, anxiety, trauma and isolation with connectedness and compassion. These drugs could literally rewire our approach to trauma, addiction and how we relate to one another.

    This article originally appeared on The Conversation. You can read it here.

  • As a major heat wave grips the eastern US, here’s how to stay safe – and the heat stroke warning signs to watch for
    Photo credit: AP Photo/Adam GrayExtreme heat can become lethal quickly. A woman fans herself while waiting in line to buy Broadway show tickets during a heat advisory in New York’s Times Square in May 2026.

    Millions of Americans are facing dangerous heat and humidity going into the July Fourth holiday as a major heat wave spreads across large parts of the central and eastern United States.

    For many people, this is the time of year for cookouts, beach trips and other outdoor activities. Soccer fans are packing into stadiums for World Cup matches. But summer also brings the risk of dangerously high temperatures in many parts of America.

    Cities as far north as Chicago and Detroit experienced a heat index over 100 degrees Fahrenheit (37.8 Celsius) in early July, and large parts of the East Coast, including New York and Washington, D.C., were bracing for similar conditions on Independence Day. Washington, D.C., and Philadelphia both canceled Independence Day parades and shortened or delayed outdoor gatherings, including the Great American State Fair on the National Mall, because of the extraordinary heat risk.

    Map shows the heat risk forecast with extreme heat in large parts of the Midwest and Mid-Atlantic region and at least major heat in the rest of the West.
    The NOAA Weather Prediction Center’s heat forecast, released July 1, 2026, shows the maximum heat risks states can expect to see at some point through Sunday, July 5. NOAA Weather Prediction Center

    I study health risks in a warming climate as a professor of public health, and I’ve seen heat become a growing concern. In the U.S., hundreds of people succumb to heat-related illnesses each year. Older adults and people in areas that historically haven’t needed air conditioning tend to see the highest rates of illnesses during heat waves, as Chicago saw in 1995 when at least 700 people died in a heat wave.

    Here are some of the key warning signs to watch for when temperatures rise – and ways to keep cool when the heat and humidity get too high.

    Heat-related deaths in the US

    Heat-related illnesses occur across a spectrum, and mild heat stress can quickly progress to life-threatening heat stroke if a person is exposed to dangerous conditions for too long.

    Mild forms of heat-related illness include heat cramps and heat rash, both of which can be caused by extensive sweating during hot conditions. Cooling the body and drinking cool fluids can help.

    When heat-related illnesses progress into heat exhaustion, the situation is more serious. Heat exhaustion includes symptoms such as dizziness, nausea, excessive sweating, feeling weak, thirst and getting a headache.

    A construction worker sits and puts his head down, still in the hot sun.
    Construction workers are often out in the heat for long periods of time, including during this heat wave in Los Angeles in July 2024. Etienne Laurent/AFP via Getty Images

    Heat exhaustion is a signal that the body is losing its ability to maintain a stable core temperature. Immediate action such as moving to a cool, ideally air-conditioned space, drinking liquids, loosening clothes and applying wet cloths are some of the recommended steps that can help keep heat exhaustion from progressing to the most dangerous form of heat-related illness, heat stroke.

    Heat stroke is a medical emergency. At this point, the body can no longer maintain a stable core temperature. A body with heat stroke can reach 106 degrees Fahrenheit or higher rapidly, and that heat can quickly damage the brain, heart and kidneys.

    An illustration showing symptoms associated with heat exhaustion, such as dizziness, heavy sweating, nausea and weakness; and with heat stroke, including confusion, dizziness and passing out.
    Signs of heat exhaustion and heat stroke, from the National Weather Service and Centers for Disease Control and Prevention. NOAA/CDC

    Typically, someone suffering heat stroke has exhausted their reserves of sweat and salt to stay cool, so sweating eventually stops during heat stroke. Their cognitive ability fails, and they cannot remove themselves from danger. Heat stroke can cause seizures or put someone into a coma as their core temperature rises. If the condition is not treated immediately, and the core temperature continues to rise, heat stroke becomes fatal.

    Because heat exhaustion can lead to heat stroke, addressing heat-related illnesses before they progress is vital.

    How to tell when the heat is too high

    Heat risk isn’t just about temperature – humidity also increases the risk of heat-related illnesses because it affects how well sweating will cool the human body when it gets hot.

    Instead of just looking at temperature when planning outdoor activities, check the heat index, which accounts for heat illness risk associated with temperature and relative humidity.

    It doesn’t take very high temperatures or very high humidity for the heat index to enter dangerous territory.

    A chart shows how humidity and temperature combine for dangerous conditions. For example, 86 degrees F at 80% humidity is a heat index of 100. 94 degrees at 45% humidity is also a heat index of 100.
    A heat index chart shows how heat and humidity combine for dangerous conditions. NOAA

    However, the heat index is still a conservative measure of the impact of heat on humans, particularly for outdoor workers and athletes at summer practices. This is because temperature measurements used in weather forecasting are taken in the shade and are not exposed to direct sunlight. If someone is outside and exposed to the direct sun, the actual heat index can be as much as 15 F higher than the heat index chart indicates.

    A more sophisticated measurement of heat effects on human health is what’s known as the wet-bulb globe temperature, which takes into account other variables, such as wind speed and cloud cover. Neither takes into account a person’s physical exertion, which also raises their body temperature, whether working at a construction site or playing soccer.

    Tips for staying safe in a heat wave

    How can you stay cool when heat waves set in? The answer depends in part on where you are, but the main points are the same:

    • Avoid strenuous outdoor activities in high temperatures if possible. If you start to feel symptoms of heat-related illnesses, drink fluids that will hydrate you. Find shade, rest, and use cool, damp cloths to lower your body temperature. If you see signs of heat stroke in someone else, call for medical help.
    • Be careful with fans. Fans can be useful if the temperature isn’t too high because they wick sweat away from the body and induce evaporative cooling. But at very high temperatures, they can accelerate heat buildup in the body and lead to dangerous conditions. If indoor temperatures reaches 95 degrees or higher, using fans can actually be dangerous and raise the risk of heat-related illnesses.
    • Find a cooling center, library or community center where you can get inside and rest in an air-conditioned space in the hottest hours. In places such as Phoenix, where high temperatures are a regular hazard, cooling centers are typically opened in summer. Northern cities are also opening cooling centers as heat waves occur there more frequently than they did in the past. Urban areas with a lot of pavement and buildings – known as heat islands – can have temperatures well above the city’s average.
    • Hydrate, hydrate, hydrate! Drink plenty of fluids, and don’t forget about the importance of electrolytes. Heat-related dehydration can occur when people sweat excessively, losing water and necessary salts from the body. Some sports drinks or rehydration fluids restore electrolytes and hydration levels.

    Older adults and people with disabilities often face higher risks from heat waves, particularly if they can’t easily move to a cooler environment. Communities and neighbors can help protect vulnerable populations by providing cooling centers and bottled water and making regular wellness checks during high heat.

    Summer can be a season of fun. Just remember the risks, keep an eye on your friends and neighbors when temperatures rise, and plan ahead so you can beat the heat.

    This article originally appeared on The Conversation. You can read it here.

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