The Scientific Roots of the Zombie Threat The Scientific Roots of the Zombie Threat

The Scientific Roots of the Zombie Threat

by Peter Smith

May 24, 2011

And a zombie apocalypse could certainly be facilitated by a food-borne brain-wasting prion, or proteinaceous infectious particle. As Ryan Bradley explains on PopSci: 

The first famous prion epidemic was discovered in the early 1950s in Papua New Guinea, when members of the Fore tribe were found to be afflicted with a strange tremble. Occasionally a diseased Fore would burst into uncontrollable laughter. The tribe called the sickness “kuru,” and by the early ’60s doctors had traced its source back to the tribe’s cannibalistic funeral practices, including brain-eating.

Theoretically, a viral prion could make its way into the brain and, provided we were administered some baking soda to prevent the prion's spread, make us very hungry:

So there is a region of the brain that's responsible for letting you know when your stomach's full. We ignore it all the time, you know, on Thanksgiving and things like that. But the ventromedial [VNM] hypothalamus, which is a region of the brain that sits below the thalamus, basically receives signals from your stomach and from your GI tract that tells you that you've had enough and it's time to stop eating... So in mice that have had the anterior ventromedial hypothalamus ablated surgically, they'll just eat and eat and eat and eat until they die, basically.

All of this is, of course, very unlikely, but taking steps to prevent a zombie apocalypse might have some real public-health benefits. There are implications here for obesity research, the perils of feeding cattle the processed remains of other animals, and the future of food-borne pathogens.

More importantly, it demonstrates how simply believing that something will be good for you can make it genuinely good for you, which certainly plays an intrinsic role for labeling foods that actually changes our habits. So perhaps when it comes to eating (and not just eating brains), a seemingly nonsensical post should be taken seriously.

Top image by Olly Moss via Threadless. Top image ©Paul Ahern. Photo of Creutzfeldt-Jakob Disease via CDC. Bottom diagram by Erin Boyle via "The skinny on neurotrophins" ©2003 Nature Neuroscience.

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The Scientific Roots of the Zombie Threat