GOOD

Flabby Lab Rats Now Fab After New Obesity Treatment

Researchers at Indiana University have essentially eliminated obesity and diabetes in lab rats with a new, three-pronged peptide.

Great news for all you overweight animals and the like suffering from obesity and diabetes: A study out of Indiana University this week in Nature Medicine details a new peptide treatment that essentially cured lab rats of both ailments by reducing blood glucose, decreasing appetite, and boosting the rate at which calories are burned on a long-term scale.


Researchers are particularly excited about the peptide because it’s a combination of three gastrointestinal hormones, and builds upon clinical results from last year, which found that pairing just two of these hormones was an effective treatment for adult-onset diabetes. Referred to as “triple agonists,” these new, extra-strength peptides reduced rodents’ body weight by around 30 percent. The double hormone of yesteryear resulted in losses about half that.

Looks like too many bread crusts for this young duckling.

“This triple hormone effect in a single molecule shows results never achieved before,” said Brian Finan, a co-first author on the study and a scientist at the Helmholtz Diabetes Center. Other researchers involved have described the findings as “unparalleled.”

An unnamed caged rodent source has described the overall mood as “elated,” pointing out that confidence levels are soaring as waistlines continue to shrink, just in time for those fast-approaching holiday parties. Word is still out on whether before and after photos will be made available to the general public, meanwhile chunkster animals everywhere are jealously awaiting their own doses of peptide power.

"Can I haz some peptides?"

“These preclinical studies suggest that, so far, this unimolecular, polypharmaceutical strategy has potential to be the most effective pharmacological approach to reversing obesity and related metabolic disorders,” the study’s abstract concludes.

Science rules.

Articles
via Michael Belanger / Flickr

The head of the 1,100-member Federal Judges Association on Monday called an emergency meeting amid concerns over President Donald Trump and Attorney General William Barr's use of the power of the Justice Department for political purposes, such as protecting a long-time friend and confidant of the president.

Keep Reading
Politics
via United for Respect / Twitter

Walmart workers issued a "wake up call" to Alice Walton, an heir to the retailer's $500 billion fortune, in New York on Tuesday by marching to Walton's penthouse and demanding her company pay its 1.5 million workers a living wage and give them reliable, stable work schedules.

The protest was partially a response to the company's so-called "Great Workplace" restructuring initiative which Walmart began testing last year and plans to roll out in at least 1,100 of its 5,300 U.S. stores by the end of 2020.

Keep Reading
Communities
via Rdd dit / YouTube

Two people had the nerve to laugh and smirk at a DUI murder sentencing in Judge Qiana Lillard's courtroom and she took swift action.

Lillard heard giggles coming from the family of Amanda Kosal, 25, who admitted to being drunk when she slammed into an SUV, killing Jerome Zirker, 31, and severely injuring his fiance, Brittany Johnson, 31.

Keep Reading
Communities