Artists Use Bacteria To ‘Grow’ Masterpieces
It’s not every day that you see a scientist create a work of art. But for the third annual Agar Art contest hosted by the American Society for Microbiology (ASM), talented microbiologists from around the world flexed their creative muscles to create intricate, ethereal paintings. Only, instead of using canvas and paint, they relied on strains of yeast, microbial bacteria, and agar plates. And what they created might cause you to rethink everything you ever thought about mold.
For those uninitiated in the mediums of microbiology, agar plates are simply petri dishes containing a thin layer of the gelatinous substance agar. Chock-full of sugar and nutrients, the agar provides a controlled, stable environment in which bacteria can grow. Scientists can then observe that growth through microscopes, allowing them to test the effectiveness of disinfectants, antibiotics, and other antibacterials.
Though the Agar Art contest wasn’t so much about preventing bacteria growth as it was channeling that growth into microbial masterpieces. Take a look at the three winners to see what I mean.
First place: “Sunset at the End” by Jasmine Temple
Microbiologist Jasmine Temple took the first-place prize with a summery sunset “painting” she created by printing tiny droplets of baker’s yeast onto an agar plate. Temple, who works as a lab technician at NYU’s Langone Medical Center, said she was inspired by a time she watched the sun set over Montauk. “I was struck by the beauty of the sunset and I thought of how beautiful it would be in the pink, blue, and purple yeast strains,” she told ASM.
Having double majored in biology and studio art as an undergrad, Temple says agar art seemed like a good way to combine both of those interests. But it was a paper postdoctoral fellow Leslie Mitchell published in 2015 about pathway assembly in yeast that really jump-started her experimentation with the unusual art form. “Two of the pathways she assembled were beta-carotene and violacien,” Temple tells GOOD. “She found that the depending on how the pathways were expressed, they yielded different colors; pinks, oranges, and yellows for the beta-carotene, and black, purples, and grays for the violacien.”
In this way, Temple is able to match an image’s color values with the colors expressed by different pathways of yeast. As Temple explains,
“I draw the image on a tablet, put it through an algorithm that matches the color values of the image I drew to the color values of the yeast we have. The algorithm gives me a kind of map that I can give with the correct pigments to a machine called an acoustic liquid handler. The machine will then print out the map with the yeast, giving tiny pinhead sized droplets that grow into the image.”
While this method requires a bit of training as well as a background in biology, Temple says anyone can be trained to make agar art using her specific process. And while we typically think of yeast as a means to make our favorite fermented products like bread and beer, Temple wants to point out you can also use yeast to make biofuel, vitamins, and pharmaceuticals.
Second place: “Finding Pneumo” by Linh Ngo
Second-place winner Linh Ngo, who works as a microbiology technologist in Ontario, told ASM her children’s love of the movie Finding Nemo inspired her microbial painting of coral. In the process, she learned about the disastrous consequences global warming poses to coral reefs. “It started as a project where I could bridge my creative side with my microbiology skills,” she told ASM, “but [it] ended up bringing awareness to the coral reefs.”
Though this wouldn’t be Ngo’s first attempt at painting with microbes. She started getting creative with control samples to entertain her coworkers, and eventually drew everything from the Toronto Blue Jays mascot to the character Olaf from Frozen. “I had a colleague ask me to draw her a minion,” Ngo tells GOOD, adding, “There really is no inspiration, I just love to draw.”
But don’t go painting your living room with bacteria just yet. As Ngo stressed to GOOD, the types of bacteria she and her coworkers use on a daily basis are not safe to handle outside of a structured lab environment. She added that, “It's important to have the knowledge of pathogens and their associated risks.” For instance, to get a textured look for her coral, Ngo used Candida tropicalis, a pathogenic strain of yeast that can cause fungal infections when mishandled.
Third place: “Dancing Microbes” by Ana Tsitsishvili
Undergraduate student Ana Tsitsishvili from Tbilisi, Georgia, drew a romantic fairytale painting largely using Staphylococcus epidermidis, which can be found naturally on our skin, and Rhodotorula mucilaginosa, a “common environmental inhabitant.” It was at the Agricultural University of Georgia that Tsitsishvili first encountered Rhodotorula mucilaginosa’s vibrant red microbes growing on a petri dish. With the encouragement of her professor, Giorgi Melashvili, Tsitsishvili began collecting samples to create a palette of different colored microbes.
According to Tsitsishvili, microbiologists have identified 1,500 species of yeast so far. These single-celled microorganisms date back hundreds of millions of years, making for some truly ancient art supplies.
Tsitsishvili was kind enough to pass along photos of her other microbial masterpieces, which you can view below. Truly, entire worlds exist beyond what the eye can see.
To see more of Tsitsishvili’s work and paintings by competitors who didn’t place this year, check out the slideshow above. Truly, a vast world exists beyond what the eye can see.
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“Marilyn Monroe. The pink shades of Kocuria and Serratia are perfect for the recreation of Warhol’s famous portrait.”
Web of Life
"For this art, bacterial culture was used as living paint to create Zentangle ® art inspired patterns representing a tangled web of life. It is fascinating to use bacteria as a way of bringing art to life and visualizing the intricate nexus of live bacteria interacting with the environment.
This agar art was created on nutrient-rich agar medium (LB broth) using two different isolates of Serratia marcescens, which is a gram-negative bacterium that produces varying levels of the red pigment ‘prodigiosin’, giving the red and orange color to the bacterial colonies."
“Chromobacterium violaceum (NCTC 9757)
Serratia marcescens (NCTC 13920)
Micrococcus luteus (NCTC 196)"
50 Shades of Antimicrobial Resistance
“This work shows multiple bacteria with two of them mating in the center of the image; this process is called conjugation and it is a mechanism involved in the dispersion of antimicrobial resistance between bacteria. The top bacterium (donor) is transferring genetic material to the bottom bacterium (recipient) through a “bridge” called a pilus. If the genetic material transferred provides resistance to antibiotics, the recipient bacterium not only becomes resistant, but also can mate with other bacteria to spread the resistance. All bacteria used to compose this art are resistant to antibiotics. Most belong to the family Enterobacteriaceae, which are part of the top 12 most dangerous superbugs listed by the World Health Organization in 2017. A yeast was also included to obtain the wrinkled aspect seen around the recipient bacterium. The red halo surrounding the pilus is due to a natural pigment released by a bacterium called Serratia marcescens. Specific compounds have been added to the agar to generate the other colors. Those compounds are uncolored, but once they are digested by the microbes, they become either pink or blue.”
Yin & Yang
"A prevailing belief in ancient Chinese philosophy is that the universe is made up entirely of opposite yet complementary forces. The embodiment of this belief is the yin and yang symbol. The red dragon in this art piece represents the powerful image of yin, while the orange phoenix represents a delicate image of yang. Red and orange colors are Serratia marcescens phenotypes. The red is the wild type strain. and the orange strain is a mutant strain derived by repeated passage to enrich for the new vivid pigment. The dragon was placed in the opposite direction with the phoenix to show the harmony and balance of their coexistence. Both are siblings because both strains were originated from one wild type parent. They have similar characteristics and growth conditions.
S. marcescens are opportunistic pathogenic Gram-negative rods. They are identified by the reddish-orange pigment in environments such as dirt or damp areas. They cause pneumonia, urinary tract infection, and blood infection in hospitals, although the incidence of these infections is very low."
Symbol of Freedom Bird
“Birds in their freedom to fly and stop wherever they like have always been a natural symbol of the freedom of the spiritually awakened human being. The person who is a free spirit is like a bird-person, a curiouso, an apu or a Garuda. A flying shaman, a kir’d noaid, is also such a being.”
By Ana Tsitsishvili
By Ana Tsitsishvili
By Ana Tsitsishvili
By Ana Tsitsishvili