“You look great!”


Um, thanks.

I have been in the hospital a number of times before due to Crohn’s disease flare-ups over the past 18 years. Sometimes I was so sick, I was unable to walk due to pain or weakness or losing blood, but never have I had to face the surgeon’s knife. That would never happen to me! No way! That only happens to other people who are really sick! I’ll never get to that point, I thought. Until I did.

The end of 2014, I was doing a show and I experienced terrific pain during a performance. I thought I may have pulled a muscle, and I thought the pain would go, but it only got worse. I ended up in the emergency room; lo and behold, it was Crohn’s.

[quote position=”right” is_quote=”true”]You can look fabulous, but can be feeling far from it.[/quote]

Even after 18 years, it always took me by surprise when I would have a flare. Apparently there was a small hole in my large intestine that the doctors managed to heal with treatment in the hospital for two weeks, avoiding surgery.

I left the hospital in November 2014, and started to feel better. So, at the end of the year, I spent some time in the States and came back to Australia at the beginning of 2015—carrying on with work and life, all going well.

Funny thing is, when you’re feeling well, you tend to forget you have Crohn’s. And this is where the danger lies, I believe. Because, when you have Crohn’s, even if you’re “feeling well,” that doesn’t necessarily mean you are.

I was back in the hospital again in June 2015, booked for another colonoscopy. As I was going in for the procedure, I bumped into my previous gastroenterologist. He said, “Hello Sylvia! How are you going?” I said, “Not too bad (why do we Aussies always under-play things?). I’m having a bit of a flare, so am going in for a colonoscopy.” He said, “Ok. Well, you look great! A bit thin, but you look great!”

I said, “Thanks.”

A Crohn’s point. You can look fabulous, but can be feeling far from it. Please don’t judge a book by its cover, friends.

I went in for the colonoscopy and my new specialist gave me the results: “Your intestines are so ruptured, we couldn’t even get the camera through; we don’t even know how you’re walking. We need to operate right away because this is potentially life-threatening.”

And there it began. I was one of those people who was apparently so sick, they needed to perform a resection surgery—removing a part of the large intestine—which turned into two surgeries, which turned into three surgeries, removing all of my large intestine, with a temporary ileostomy—the dreaded bag.

This, by the way, is not standard.

Apparently a resection surgery is a resection surgery. And that’s it. You’re in. You’re out. You go home.

My first surgery, however, broke away in my body after a week of recovery. Truly horrific. I have never been in so much pain and I have never felt so frightened in my life. The surgeons had to do an emergency second operation, removing the remainder of my large intestine, and that’s where I ended up with the ileostomy—the bag. Thankfully the ileostomy was only temporary. This sort of major surgical complication only ever happened to the surgeon once before. Also, during my six-week stay in the hospital (which was only meant to be two weeks max) there were further complications. In fact, medical students came around to have a look at me, as a study on “What can go wrong when operating on Crohn’s patients.” Great. They were, by the way, quite strapping doctors, so that was a highlight. I, however, wasn’t in my best form to say the least. I was looking exactly as I was feeling.

[quote position=”left” is_quote=”true”]Your intestines are so ruptured, we couldn’t even get the camera through.[/quote]

Crohn’s can be very tricky, in a number of ways. It can even fool the patient. You may look great. Doctors can even say you look great. You may think you’re feeling great. And that’s hard to monitor, because with chronic illness, you can become so accustomed to being run down and experiencing pain on a regular basis, that your tolerance for pain is actually quite high compared to others not experiencing chronic illness.

Thankfully, now one year later, I am doing well. I’m on a new medication, Humira, which has helped put the disease into remission. And, I hope to continue to stay in remission. And, I know I will never let myself get to that point ever again. The moment there is a hint of anything, I am going straight to the doctor.

So, my learning from all of this is—take this disease incredibly seriously. I don’t think I ever really did, not to the extent I should have. Being a “bit sick,” for me, was the norm. Until now. Please, friends with Crohn’s and family members of those with Crohn’s, don’t judge the disease from how you may look or feel, even if you feel great. Monitor yourself consistently with doctors, specialists—talk about Crohn’s, go to support groups. Ask questions, share. This disease is a very real thing. And, it can take you completely off guard. Lord knows it did with me.

  • Could you survive The Oregon Trail? An emergency medicine doctor offers tips on how to not die in the great outdoors
    You might not die of dysentery on the trail these days, but there is still plenty of danger outdoors. Different_Brian/iStock via Getty Images Plus
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    Could you survive The Oregon Trail? An emergency medicine doctor offers tips on how to not die in the great outdoors

    The old computer game’s hazards still hold lessons for modern hikers, even with smartphones, better medicine and sturdier equipment.

    If you grew up in the United States in the 1980s or ’90s, chances are you remember The Oregon Trail. For many like me, it was our first computer game and our first introduction to wilderness survival. We hunted buffalo, forded rivers, broke wagon wheels and, of course, learned about dysentery years before Google even existed, all while hoping our group would make it to Oregon City alive.

    Lately, the game has found a second life. Nostalgic social media posts, memes and updated versions of the game have introduced The Oregon Trail to a new generation while reminding millennials just how unforgiving that grainy computer screen journey could be.

    As a physician who specializes in emergency and wilderness medicine, I started thinking about how much of what the game taught me about surviving in the wilderness still applies today. After all, modern hikers and campers have access to tools the pioneers could never have imagined.

    Surprisingly, I’d argue that more lessons from The Oregon Trail hold up than you might think.

    Clean water is crucial

    The Oregon Trail game made dysentery famous for an entire generation. Fortunately, advances in sanitation, hand hygiene and antibiotics have made large outbreaks like those that wagon trains and military camps experienced much less common, at least in the United States.

    That doesn’t mean gastrointestinal illnesses have disappeared. Traveler’s diarrhea and cholera are still an important cause of illness around the world. Untreated water, poor hand hygiene and contaminated food can still derail any trip.

    Simple habits such as purifying drinking water, washing hands before meals and after using the bathroom, and practicing good camp hygiene remain some of the easiest ways to stay healthy outdoors.

    Steaming pot of water on small portable stove on top of a plank of wood in a forest
    Boiling is the most reliable way to purify your water. Veronika Lunina/iStock via Getty Images

    Water purification is important with wilderness travel in the United States and in many areas of the world. There are many easy and cost-effective ways to purify water, such as boiling, filtration and treating with chemical disinfectants. Each method has its benefits and downsides.

    Boiling is often the most accessible method. While it can kill bacteria, viruses and parasites, it will not remove water contaminants such as heavy metals, including lead and arsenic, or industrial contamination such as pesticides. Consider boiling your water for at least one to three minutes, depending on your altitude, to purify it. Water filtration is an easy option for backpackers but is less effective at removing viruses.

    If you’re unable to boil your water, another way to ensure water safety is to filter it, then use another method to disinfect it.

    Respect all waterways

    You may no longer have to ford the river with oxen, but rivers, lakes and other bodies of water present unique hazards that outdoor adventure enthusiasts can overlook.

    Moving water can be more dangerous than people realize. Even the best swimmers can drown in rip currents.

    Cross bodies of water only when absolutely necessary. Avoid any water crossings after recent rainfall, as the water level often rises and the current can be faster and stronger. Submerged objects – rocks, fallen trees and other debris – as well as changing weather, flash flooding and strong currents can make crossing more dangerous.

    If possible, use a Coast Guard-approved life jacket when you’re crossing water or on a boat.

    Be ready to go the distance

    It’s not just a broken wagon axle that can send a trip sideways. One thing The Oregon Trail captured well is how distance changes everything. A sprained ankle in a city usually means an inconvenient trip home or to the doctor, but a sprained ankle 5 miles from the trailhead may mean that someone will need to carry you. The same is true for other common wilderness concerns, such as dehydration, heat illness, infections or even blisters.

    Preparation is about packing a first aid kit and thinking ahead. Ask yourself what you would do if your hike took twice as long as expected or if you unexpectedly had to spend the night outside. Research your route and carry more food and water than you think you’ll need. Check the weather and be prepared for it to change, with extra clothing and options for rain.

    Group of hikers walking through forest, away from camera
    It’s dangerous to go alone. FG Trade/E+ via Getty Images

    No one tackled the Oregon Trail alone because it meant you would not survive. There is a lesson here in solo travel and solo mountaineering.

    Traveling alone means that a minor injury such as a sprained ankle could mean crawling to the trailhead to call for help or waiting until you are identified as missing. If you cannot find someone to travel with you, provide an itinerary and travel location to a trusted person. Make sure they know when you should be returning and plan to check in. If you do not return as expected, they can call for help.

    Respect the wildlife

    Large animals still pose a threat across the country. While there may be fewer bison than previously seen on the Oregon Trail, animals in nature deserve respect.

    No selfie is worth being attacked by a brown bear. If you see a dangerous wild animal, avoid approaching and immediately leave the area.

    Venomous snakes are present throughout much of the United States and continue to cause significant injury and death around the world. If someone is bitten, please don’t try to cut the wound or suck out the venom. Instead, keep the person calm, minimize unnecessary movement, and focus on getting them to professional medical care. Antivenom is available in many major hospitals in the United States.

    Even smaller and more docile animals such as deer and squirrels should not be fed. It is dangerous for an animal to get used to receiving food from humans. Additionally, animals carry diseases, such as rabies and leptospirosis, that can be fatal to people.

    Don’t attempt to get close to any animals, no matter how calm or asleep the animal appears to be.

    Technology is a backup, not a plan

    One of the biggest differences between today’s outdoor adventures and those of the Oregon Trail is the ability to communicate.

    Cellphones, GPS apps and emergency beacons have made it possible to call for help from places that were once completely isolated. However, while those devices are incredibly valuable, they shouldn’t encourage you to take bigger risks, as help may be far away, slow to arrive, and injuries in the wilderness can be fatal.

    Travelers can use a smartphone with GPS capacity to avoid getting lost, but downloading any needed maps for offline use can help prevent lack of service from derailing your trip.

    Additionally, an unlocked smartphone that isn’t restricted to one carrier is a great way to store and communicate critical data, such as travel plans and copies of your medical history.

    Person leaning over map spread over a rock beside a bike, plains stretching into the background
    Having an offline map is critical when going somewhere remote. Grant Ordelheide/Aurora Photos/Cavan via Getty Images

    Every environment has its own hazards

    The Oregon Trail travelers worried about river crossings, disease and harsh weather. Today’s hikers face different challenges depending on where they are.

    Desert hikers may struggle with extreme heat and dehydration. Mountain travelers face rapidly changing weather, lightning and high altitude. And coastal explorers can face problems such as riptides, waves, cliffs and unexpected rocky surfaces.

    Altitude illness is often unpredictable and can sneak up on you. Most people experience acute mountain sickness within 24 hours of ascent, developing symptoms such as headache, fatigue, nausea or problems with sleep. Any confusion, difficulty walking, shortness of breath or coughing up significant phlegm should prompt an immediate descent.

    There are commonly used prescription medications to help prevent and treat altitude illness. The mountain will always be waiting for your next attempt.

    Some lessons survive every software update

    Part of what made The Oregon Trail game memorable is that every decision mattered. Success often depended less on luck than on planning ahead, and that lesson still applies.

    When people ask me what one emergency medicine skill everyone should know before heading outdoors, my answer is usually preparation. Thoughtful planning prevents far more emergencies than any single piece of equipment.

    For people who spend a lot of time outdoors, I also recommend taking a wilderness first aid course. These courses teach practical skills to provide medical care in a wilderness environment.

    Nature is no less powerful or unforgiving than it was on the Oregon Trail, and treating it with respect is essential. Combining advances in modern medicine with thoughtful preparation helps stack the odds in your favor so that, just as every Oregon Trail player hoped, everyone in the party makes it to the end.

    This article originally appeared on The Conversation. You can read it here.
  • Your cells keep a record of every workout you’ve ever done – and those gains persist even after a break from exercise
    Photo credit: Williams+Hirakawa/The Image Bank via Getty Images – Your body retains the benefits of exercise even when you need to hit pause.
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    Your cells keep a record of every workout you’ve ever done – and those gains persist even after a break from exercise

    New research suggests muscle and liver cells retain a memory of exercise, offering hope when injury or life interrupts a workout routine.

    Have you ever taken months off training – maybe due to an injury, a new baby or crushing work deadlines – and come back convinced you were starting from zero?

    Research from our team has some good news: At the cellular level, you probably weren’t.

    We found that muscle and liver cells store memories from every training session in ways that may help improve endurance, control blood sugar levels and even slow weight regain after inactivity.

    Use it or lose it? Maybe not

    For most of the past century, long before fad diets and fancy workout trends took off, exercise was considered one of the most effective lifestyle changes to lower the risk of heart disease, Type 2 diabetes, several cancers and early death for people of all ages. But people typically understood exercise as something whose beneficial effects fade away over time: You use it or lose it.

    When you stop training, your maximum oxygen uptake, muscle gains and insulin sensitivity drift back to where they started, often within weeks. Physical activity guidelines are built on this fact, which is why they emphasize consistency above all else.

    Consistency, however, is a luxury that roughly 3 in 4 American adults aren’t able to enjoy. People can experience injuries, illness, pregnancy or jobs that limit their time for or ability to exercise. If adaptation really resets, every time you step into the gym would be as if you’ve never been there before. But that scenario doesn’t match what coaches and returning athletes typically describe: In practice, people who have trained before can get fit again faster than those who haven’t undergone similar training.

    In recent years, however, scientists have started challenging the concept of “use it or lose it.” New research hints that your cells might keep a record of your training history so all of your gains are not completely lost.

    More than muscle

    We are exercise physiologists who study how cells remember exercise. Our lab and others have shown that the body is able to store a form of exercise memory across different organs.

    To study how this exercise memory works, our team of researchers use an ON-OFF-ON exercise training protocol in mice, which involves an initial four- to eight-week training period, followed by detraining – a period of no exercise – and a second training bout. This method allows us to examine how cells form a memory of exercise, maintain a record of exercise through detraining, and recall memories of prior training when exposed again to exercise.

    Using this strategy, our team found that skeletal muscle memory accelerates muscle growth. Compared to mice with no training history, mice who retrained grew bigger muscles, and the individual muscle fibers inside those muscles grew too. Larger muscle fibers meant that the working cells were themselves getting bigger, rather than the surrounding tissue.

    Looking more closely at these muscle cells, we found that retrained muscle is better at matching energy production to demand – meaning, the muscles were better at drawing from energy stores when it’s needed most – and this ability persists without further exercise. This memory held even when the mice ate a high-fat diet, suggesting that prior training can still offer benefits even when diet is working against those gains.

    Muscle isn’t the only body part that learns from exercise. Working muscle needs fuel, and the liver supplies it during and after training sessions.

    My colleagues and I found that liver cells also store exercise memory and uses it to feed muscle more efficiently. In both mice and people who trained, stopped, then trained again, their livers released higher levels of a family of enzymes called carboxylesterases. These enzymes chop up lipids circulating in the blood, delivering fat in a form that muscle can take up and burn as it grows.

    A record that outlives you

    Recorded cellular memories of exercise may even be passed down to future generations.

    In mice, we found that three to four weeks of maternal and paternal endurance exercise can have a lasting effect on their offspring. Compared to offspring born to sedentary parents, parental exercise granted protection against poor blood sugar levels and excess weight gain for an entire year after birth.

    Researchers have hypothesized numerous ways that prenatal exercise may affect offspring. For example, maternal exercise might allow offspring to spend more time developing in the womb or lead parents to producer higher quality milk.

    But there remains much to be discovered on how parents influence the health of their children and whether their lifestyle could provide a fitness advantage across generations.

    Every cell remembers

    Biology has traditionally granted memory to a short list of cells. Neurons store memory in the connections between them. Immune cells store memory so they can recognize pathogens faster and more strongly the next time they encounter them.

    Researchers previously considered all other cells to be memoryless; a cell responds to a signal, then returns to baseline without keeping a record of that interaction. But that assumption is now coming apart.

    Skin stem cells can keep a record of inflammation, allowing them to heal a new wound faster months later. Human fat cells keep a record of obesity that persists even after substantial weight loss, which may account for why you gain weight faster when switching back to a high-calorie diet – the so-called yo-yo effect.

    We propose that every cell in the body remembers exercise, regardless of how little or how much someone trains. The question is how long these records are stored and whether researchers could prolong or expand each cell’s storage capacity. Better understanding of how cells learn and remember exercise, where they store memories and how those memories are preserved could help improve exercise guidelines for those who cannot exercise for prolonged or consistent periods of time.

    To be clear, none of these findings are evidence for skipping the gym; nothing in our data suggests the effects of past training can substitute for present training. But there is hope that the work you put into getting in shape isn’t completely lost over time.

    Somewhere, deep in your cells, there is a record waiting to be replayed the next time you lace up your running shoes, pick up a pair of dumbbells or want to fulfill a New Year’s resolution.

    This article originally appeared on The Conversation. You can read it here.
  • Friendship is built over time, through ordinary moments – I teach lonely college students to notice them
    Nearly 6 in 10 college students said in 2026 that they felt lonely sometimes or always. Denis Novikov/iStock/Getty Images Plus
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    Friendship is built over time, through ordinary moments – I teach lonely college students to notice them

    A college course explores how small, everyday interactions grow into lasting connections.

    Professor of Political Science and Director of the Center for Applied Civic Leadership, Coastal Carolina University

    The first skill I learned when I became a political science professor nearly 20 years ago was how to quiet a room full of chatty undergraduates.

    These days, I often walk into a silent room, with students staring at their phones and barely acknowledging the classmates beside them.

    As I read more about the United States’ loneliness crisis, I began noticing a version of it among my students.

    In a 2026 national survey of over 40,000 college students, nearly 6 in 10 said they felt lonely sometimes or always. At the same time, federal time-use data show that the share of Americans who socialized in person with family, friends or others on an average day fell from 38% in 2015 to 30% in 2025.

    Those and similar other studies capture a familiar contradiction seen on college campuses like my own: Many new students want close relationships, but feel anxious about initiating them and have had little practice sustaining them.

    I realized that my students rarely spoke to one another, and went entire semesters without learning their classmates’ names. Many students seemed unsure how to cross the few feet between them and their peers and make the social connection they craved.

    I designed a freshman honors seminar, “Friendship & Society,” around this uncertainty, combining the academic study of friendship with practical exercises in forming and sustaining it.

    Two women walk closely together down a stone path with red brick pillars on either side of them.
    College students in this class learn about how positive social interactions activate the brain’s reward system while isolation triggers a stress response. Klaus Vedfelt/Digital Vision via Getty Images

    Understanding friendship

    In this course, students examine how an initial exchange can develop into friendship through repeated contact and shared time, and why many potential connections never progress into a lasting friendship.

    They consider how friends help shape identity and memory, whether old friends are owed continued loyalty after their lives diverge and whether a friendship can remain meaningful after it ends.

    Students also look at how friendship can have strong effects on physical and mental health, making it what I believe is an overlooked public health issue. Friendships can also help shape people’s broader sense of belonging in a community, building the social trust that civic life depends on.

    Students test those questions through 10 “Friendship Practices,” a series of experiential activities I designed. Students are asked to share a meal with classmates or visit a public gathering place like a café or lounge to see how these settings can encourage conversation. During a “friendship safari,” small groups walk across campus, noting where conversations begin and where students pass one another without speaking.

    In private journal entries and submitted reflections, students record what they expected from each situation, and what happened when they tried to form connections. They make a short film telling a story of friendship on campus and end with a friendship memoir tracing how their own relationships and expectations changed during their first semester of college.

    Diving into friendship

    Students read “Stay True,” a memoir about a friendship between author Hua Hsu and his classmate Ken that shapes Hsu’s sense of himself long after his friend’s death.

    Neuroscientist Ben Rein’s book “Why Brains Need Friends” explains the biology of connection and isolation, and shows how positive interactions activate the brain’s reward system while isolation triggers a stress response.

    Students also read longform journalism, social science research, public health reports and political philosophy on aspects of loneliness. They also watch TED Talks and films that explore how a brief encounter with a stranger can, over time, become a friendship.

    Lessons learned

    Students learn that a friendship is built from countless moments that may feel meaningless while they are happening. An unremarkable meal, or a conversation that fills 10 spare minutes rarely feels consequential on its own.

    Over time, those moments build relational capital, meaning the shared trust and history friends can draw on when life becomes difficult or a disagreement needs repairing.

    That reserve reaches beyond a single relationship. Communities become more connected when people have accumulated enough ordinary experience together to trust one another and keep showing up.

    Four young women smile and pose as they lift one of the women, wearing a black graduation gown and carrying flowers, in the air.
    Individual, ordinary moments with peers over time can build and help form a friendship. Jeff Gritchen/MediaNews Group/Orange County Register via Getty Images

    By the end of the course, students can weigh different kinds of evidence about how friendships form, develop and sometimes fade. They also become better able to start a conversation, recognize which public spaces make it easier to meet and spend time with others, and identify habits that help relationships deepen over time.

    They finish with a clearer sense of how relationships take shape and how their own choices contribute to the communities forming around them.

    Uncommon Courses is an occasional series from The Conversation U.S. highlighting unconventional approaches to teaching.

    This article originally appeared on The Conversation. You can read it here.

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